J
José Schneider
Researcher at University of Valladolid
Publications - 121
Citations - 2824
José Schneider is an academic researcher from University of Valladolid. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 26, co-authored 116 publications receiving 2230 citations. Previous affiliations of José Schneider include King Juan Carlos University & University of the Basque Country.
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Journal ArticleDOI
Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine
TL;DR: Among MSCs, human uterine cervical stem cells (hUCESCs) may be a good candidate for obtaining secretome-derived products, and regulatory requirements for manufacturing and quality control will be necessary to establish the safety and efficacy profile of these products.
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Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses.
Luis A. Costa,Noemi Eiro,María Fraile,Luis O. González,Jorge Saa,Pablo Garcia-Portabella,Belén Vega,José Schneider,Francisco J. Vizoso +8 more
TL;DR: To attain a more personalized and precise medicine, a correct selection of MSC is mandatory, based on their functional potential, as well as the need to integrate all the existing information to achieve an optimal improvement of M SC features in the artificial niche.
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Nup88 mRNA overexpression is associated with high aggressiveness of breast cancer.
David Agudo,Francisco Gómez-Esquer,Fernando Martínez-Arribas,Mariá José Núñez-Villar,Marina Pollán,José Schneider +5 more
TL;DR: High Nup88 mRNA expression levels correlated significantly with ductal and tubular histology, as well as the most important ominous clinical prognostic factor, axillary node invasion, and an inverse correlation with expression of the H‐MAM (mammaglobin) gene, a marker of low biologic and clinical aggressiveness of breast cancer.
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Positive correlation between the expression of X‐chromosome RBM genes (RBMX, RBM3, RBM10) and the proapoptotic Bax gene in human breast cancer
Fernando Martínez-Arribas,David Agudo,Marina Pollán,Francisco Gómez-Esquer,Gema Díaz-Gil,Raul Lucas,José Schneider +6 more
TL;DR: It seems that the X‐chromosome, through its RBM genes, plays a formerly unknown role in the regulation of programmed cell death (apoptosis) in breast cancer.
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Mesenchymal Stem Cells in Homeostasis and Systemic Diseases: Hypothesis, Evidences, and Therapeutic Opportunities.
Francisco J. Vizoso,Noemi Eiro,Luis Costa,Paloma Esparza,Mariana Landin,Patricia Diaz-Rodriguez,José Schneider,Roman Perez-Fernandez +7 more
TL;DR: This scenario opens the possibility for the use of secretome-derived products from MSCs as new therapeutic agents in order to restore tissue homeostasis, instead of the classical paradigm “one disease, one drug”.