José Tomás Ramos

TL;DR: Decisions about starting antiretroviral therapy can now be based on a recent large meta‐analysis of the predictive value of CD4 and HIV RNA viral load in nearly 4000 untreated children, which is discussed in these updated guidelines.

TL;DR: The CD4/CD8 ratio may identify patients with higher immunoactivation despite ART, and is associated with higher frequencies of activated, senescent and activated/exhausted CD4+and CD8+ T-cells, and a skewed T-cell phenotype from naive toward effector memory which persisted after the multivariate analysis.

TL;DR: Serodiscordant couples attaining natural pregnancy are exposed to a negligible risk of sexual transmission of HIV when the infected partner presents with complete suppression of plasma viremia while receiving highly active antiretroviral therapy (HAART).

TL;DR: In this paper, the authors considered the incidence of individual AIDS-defining illnesses (ADI) at higher CD4 counts, relevant on a population level for monitoring and resource allocation.

TL;DR: To produce European Guidelines for the use of antiretroviral therapy in HIV‐infected children, the aim was to produce guidelines that guided the development of and continued use of ART in children with HIV.