C
Carmen de Mendoza
Researcher at Carlos III Health Institute
Publications - 246
Citations - 6169
Carmen de Mendoza is an academic researcher from Carlos III Health Institute. The author has contributed to research in topics: Hepatitis C & Viral load. The author has an hindex of 42, co-authored 226 publications receiving 5638 citations.
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Journal ArticleDOI
Prevalence of Drug-Resistant HIV-1 Variants in Untreated Individuals in Europe: Implications for Clinical Management
Annemarie M. J. Wensing,David A. M. C. van de Vijver,Gioacchino Angarano,Birgitta Åsjö,Claudia Balotta,Enzo Boeri,Ricardo Jorge Camacho,Maire-Laure Chaix,Dominique Costagliola,Andrea De Luca,Inge Derdelinckx,Zehava Grossman,Osamah Hamouda,Angelos Hatzakis,Robert Hemmer,Andy I. M. Hoepelman,Andrzej Horban,Klaus Korn,Claudia Kücherer,Thomas Leitner,Clive Loveday,E MacRae,I Maljkovic,Carmen de Mendoza,Laurence Meyer,Claus J. Nielsen,Eline L. M. Op de Coul,Vidar Ormaasen,D Paraskevis,Luc Perrin,Elisabeth Puchhammer-Stöckl,Lidia Ruiz,Mika Salminen,Jean-Claude Schmit,François Schneider,Rob Schuurman,Vincent Soriano,G Stanczak,Maja Stanojevic,Anne-Mieke Vandamme,Kristel Van Laethem,Michela Violin,Karin Wilbe,Sabine Yerly,Maurizio Zazzi,Charles A. Boucher +45 more
TL;DR: In this paper, the authors determined the baseline rate of drug resistance in 2208 therapy-naive patients recently and chronically infected with HIV-1 from 19 European countries during 1996-2002.
Journal ArticleDOI
Natural pregnancies in HIV-serodiscordant couples receiving successful antiretroviral therapy.
Pablo Barreiro,Jorge del Romero,Manuel Leal,Victoria Hernando,Román Asencio,Carmen de Mendoza,Pablo Labarga,Marina Núñez,José Tomás Ramos,Juan González-Lahoz,Vincent Soriano +10 more
TL;DR: Serodiscordant couples attaining natural pregnancy are exposed to a negligible risk of sexual transmission of HIV when the infected partner presents with complete suppression of plasma viremia while receiving highly active antiretroviral therapy (HAART).
Journal ArticleDOI
Evaluation of Eight Different Bioinformatics Tools To Predict Viral Tropism in Different Human Immunodeficiency Virus Type 1 Subtypes
Carolina Garrido,Vanessa Roulet,Natalia Chueca,Eva Poveda,Antonio Aguilera,Katharina Skrabal,Natalia Zahonero,Silvia Carlos,Federico García,Jean Louis Faudon,Vincent Soriano,Carmen de Mendoza +11 more
TL;DR: While inferences of HIV-1 coreceptor usage using genotypic tools seem to be reliable for clade B viruses, their performances are poor for non-B subtypes, in which they particularly fail to detect X4 variants.
Journal ArticleDOI
The calculated genetic barrier for antiretroviral drug resistance substitutions is largely similar for different HIV-1 subtypes
David A. M. C. van de Vijver,Annemarie M. J. Wensing,Gioacchino Angarano,Birgitta Åsjö,Claudia Balotta,Enzo Boeri,Ricardo Jorge Camacho,Marie-Laure Chaix,Dominique Costagliola,Andrea De Luca,Inge Derdelinckx,Zehava Grossman,Osamah Hamouda,Angelos Hatzakis,Robert Hemmer,Andy I. M. Hoepelman,Andrzej Horban,Klaus Korn,Claudia Kücherer,Thomas Leitner,Clive Loveday,E MacRae,I Maljkovic,Carmen de Mendoza,Laurence Meyer,Claus J. Nielsen,Eline L. M. Op de Coul,Vidar Ormaasen,D Paraskevis,Luc Perrin,Elisabeth Puchhammer-Stöckl,Lidia Ruiz,Mika Salminen,Jean-Claude Schmit,François Schneider,Rob Schuurman,Vincent Soriano,G Stanczak,Maja Stanojevic,Anne-Mieke Vandamme,Kristel Van Laethem,Michela Violin,Karin Wilbe,Sabine Yerly,Maurizio Zazzi,Charles A. Boucher +45 more
TL;DR: Based on the calculated genetic barrier, the rate of drug resistance development may be similar for different HIV-1 subtypes, and protease inhibitor resistance could be enhanced in particular subtypes once the relevant major substitutions are selected.
Journal ArticleDOI
Impact of Human Immunodeficiency Virus Type 1 (HIV-1) Genetic Diversity on Performance of Four Commercial Viral Load Assays: LCx HIV RNA Quantitative, AMPLICOR HIV-1 MONITOR v1.5, VERSANT HIV-1 RNA 3.0, and NucliSens HIV-1 QT
Priscilla Swanson,Carmen de Mendoza,Yagnya Joshi,Alan Golden,Richard L. Hodinka,Vincent Soriano,Sushil G. Devare,John Hackett +7 more
TL;DR: Analysis of nucleotide mismatches at the primer/probe binding sites for Monitor v1.5, NucliSens, and LCx assays revealed that performance characteristics reflected differences in the level of genetic conservation within the target regions.