J
Juan Pedro Kusanovic
Researcher at National Institutes of Health
Publications - 251
Citations - 19185
Juan Pedro Kusanovic is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Pregnancy & Amniotic fluid. The author has an hindex of 65, co-authored 246 publications receiving 17350 citations. Previous affiliations of Juan Pedro Kusanovic include Detroit Medical Center & Wayne State University.
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Journal ArticleDOI
Placental growth hormone is increased in the maternal and fetal serum of patients with preeclampsia
Pooja Mittal,Jimmy Espinoza,Sonia S. Hassan,Juan Pedro Kusanovic,Samuel Edwin,Jyh Kae Nien,Francesca Gotsch,Nandor Gabor Than,Offer Erez,Shali Mazaki-Tovi,Roberto Romero +10 more
TL;DR: In this paper, the maternal serum concentrations of Placental Growth Hormone (PGH) change in women with preeclampsia, women with PE who deliver a small for gestational age neonate (PE + SGA), and those with SGA alone.
Journal ArticleDOI
An episode of preterm labor is a risk factor for the birth of a small-for-gestational-age neonate
Jimmy Espinoza,Juan Pedro Kusanovic,Chong Jai Kim,Chong Jai Kim,Yeon Mee Kim,Yeon Mee Kim,Jung Sun Kim,Sonia S. Hassan,Sonia S. Hassan,Francesca Gotsch,Luís F. Gonçalves,Luís F. Gonçalves,Offer Erez,Lara A. Friel,Eleazar Soto,Roberto Romero,Roberto Romero +16 more
TL;DR: It is proposed that insults to the fetoplacental unit may be resolved by either irreversible preterm parturition or restriction of fetal growth, which suggests that an episode of false preterm labor is not a benign condition.
Journal ArticleDOI
Acute pyelonephritis during pregnancy changes the balance of angiogenic and anti-angiogenic factors in maternal plasma.
Tinnakorn Chaiworapongsa,Roberto Romero,Francesca Gotsch,Juan Pedro Kusanovic,Pooja Mittal,Sun Kwon Kim,Offer Erez,Edi Vaisbuch,Shali Mazaki-Tovi,Chong Jai Kim,Zhong Dong,Lami Yeo,Sonia S. Hassan +12 more
TL;DR: It is concluded that despite high plasma inflammatory cytokine concentrations, acute systemic inflammation in pregnancy has a different angiogenic/anti-angiogenic profile than that of PE.
Journal ArticleDOI
A decrease in maternal plasma concentrations of sVEGFR-2 precedes the clinical diagnosis of preeclampsia.
Tinnakorn Chaiworapongsa,Tinnakorn Chaiworapongsa,Roberto Romero,Roberto Romero,Adi L. Tarca,Adi L. Tarca,Juan Pedro Kusanovic,Juan Pedro Kusanovic,Francesca Gotsch,Pooja Mittal,Pooja Mittal,Sun Kwon Kim,Sun Kwon Kim,Edi Vaisbuch,Edi Vaisbuch,Shali Mazaki-Tovi,Shali Mazaki-Tovi,Offer Erez,Offer Erez,Zhong Dong,Chong Jai Kim,Chong Jai Kim,Lami Yeo,Lami Yeo,Sonia S. Hassan,Sonia S. Hassan +25 more
TL;DR: A lower maternal plasma sVEGFR-2 concentration precedes the development of preeclampsia, both term and preterm.
Journal ArticleDOI
Amniotic fluid soluble human leukocyte antigen-G in term and preterm parturition, and intra-amniotic infection/inflammation.
Juan Pedro Kusanovic,Roberto Romero,Cristiano Jodicke,Shali Mazaki-Tovi,Edi Vaisbuch,Offer Erez,Pooja Mittal,Francesca Gotsch,Tinnakorn Chaiworapongsa,Sam Edwin,Percy Pacora,Sonia S. Hassan +11 more
TL;DR: AF sHLA-G concentrations are elevated in preterm parturition associated to IAI as well as in histologic chorioamnionitis, which is proposed to participate in the regulation of the host immune response against intra-amniotic infection.