J
Juan Pedro Kusanovic
Researcher at National Institutes of Health
Publications - 251
Citations - 19185
Juan Pedro Kusanovic is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Pregnancy & Amniotic fluid. The author has an hindex of 65, co-authored 246 publications receiving 17350 citations. Previous affiliations of Juan Pedro Kusanovic include Detroit Medical Center & Wayne State University.
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Tissue factor activity in women with preeclampsia or SGA: a potential explanation for the excessive thrombin generation in these syndromes.
Offer Erez,Offer Erez,Roberto Romero,Edi Vaisbuch,Edi Vaisbuch,Nandor Gabor Than,Juan Pedro Kusanovic,Juan Pedro Kusanovic,Shali Mazaki-Tovi,Shali Mazaki-Tovi,Francesca Gotsch,Pooja Mittal,Pooja Mittal,Zhong Dong,Zhong Dong,Tinnakorn Chaiworapongsa,Tinnakorn Chaiworapongsa,Chong Jai Kim,Chong Jai Kim,Chia Ling Nhan-Chang,Chia Ling Nhan-Chang,Chia Ling Nhan-Chang,Sun Kwon Kim,Sun Kwon Kim,Lami Yeo,Lami Yeo,Moshe Mazor,Sonia S. Hassan,Sonia S. Hassan +28 more
TL;DR: Changes in the activity of tissue factor and TFPI in the plasma of women with preeclampsia and small for gestational age neonate are proposed to be responsible for the increased in-vivo thrombin generation observed in this obstetrical syndrome.
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Fetal death: a condition with a dissociation in the concentrations of soluble vascular endothelial growth factor receptor-2 between the maternal and fetal compartments.
Tinnakorn Chaiworapongsa,Juan Pedro Kusanovic,Zeynep Alpay Savasan,Shali Mazaki-Tovi,Sun Kwon Kim,Edi Vaisbuch,Adi L. Tarca,Pooja Mittal,Giovanna Ogge,Ichchha Madan,Zhong Dong,Lami Yeo,Sonia S. Hassan,Roberto Romero +13 more
TL;DR: Pregnancies with a fetal death, at the time of diagnosis, are characterized by a decrease in the maternal plasma concentration of sVEGFR-2, but an increase in the amniotic fluid concentration of this protein, which seems to be a common feature of fetal death.
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Pyelonephritis during pregnancy: A cause for an acquired deficiency of protein Z
Jyh Kae Nien,Roberto Romero,Debra Hoppensteadt,Offer Erez,Jimmy Espinoza,Eleazar Soto,Juan Pedro Kusanovic,Francesca Gotsch,Chong Jai Kim,Pooja Mittal,Jawed Fareed,Joaquin Santolaya,Tinnakorn Chaiworapongsa,Samuel Edwin,Beth L. Pineles,Sonia S. Hassan +15 more
TL;DR: The median maternal plasma protein Z concentration was significantly lower in patients with pyelonephritis during pregnancy than in patientsWith normal pregnancies.
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Amniotic Fluid and Umbilical Cord Plasma Corticotropin-Releasing Factor (CRF), CRF-Binding Protein, Adrenocorticotropin, and Cortisol Concentrations in Intraamniotic Infection and Inflammation at Term
Pasquale Florio,Roberto Romero,Tinnakorn Chaiworapongsa,Juan Pedro Kusanovic,Michela Torricelli,Phil J. Lowry,Felice Petraglia +6 more
TL;DR: Amniotic fluid and umbilical cord plasma CRF and CRF-BP concentrations are increased in women with spontaneous labor at term and IAI, playing a pivotal role in limiting the inflammatory process and thus avoiding an overactivation of the fetal/placental hypothalamus-pituitary-adrenal axis at birth.
Journal ArticleDOI
Evidence for differential regulation of the adipokine visfatin in the maternal and fetal compartments in normal spontaneous labor at term.
Shali Mazaki-Tovi,Roberto Romero,Edi Vaisbuch,Sun Kwon Kim,Juan Pedro Kusanovic,Tinnakorn Chaiworapongsa,Pooja Mittal,Zhong Dong,Percy Pacora,Lami Yeo,Sonia S. Hassan +10 more
TL;DR: The observations reported herein support the view that there are fundamental differences in the endocrine and metabolic adaptations in normal labor at term and preterm labor.