J
Juan Pedro Kusanovic
Researcher at National Institutes of Health
Publications - 251
Citations - 19185
Juan Pedro Kusanovic is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Pregnancy & Amniotic fluid. The author has an hindex of 65, co-authored 246 publications receiving 17350 citations. Previous affiliations of Juan Pedro Kusanovic include Detroit Medical Center & Wayne State University.
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Journal ArticleDOI
Normal and abnormal transformation of the spiral arteries during pregnancy.
Jimmy Espinoza,Roberto Romero,Yeon Mee Kim,Juan Pedro Kusanovic,Sonia S. Hassan,Offer Erez,Francesca Gotsch,Nandor Gabor Than,Zoltán Papp,Chong Jai Kim +9 more
TL;DR: The anatomy and physiology of the uterine circulation is reviewed, with emphasis on the remodeling of spiral arteries during normal pregnancy, and the timing and anatomical pathways of trophoblast invasion of the spiral arteries.
Journal ArticleDOI
Metabolomics in premature labor: a novel approach to identify patients at risk for preterm delivery.
Roberto Romero,Shali Mazaki-Tovi,Shali Mazaki-Tovi,Edi Vaisbuch,Edi Vaisbuch,Juan Pedro Kusanovic,Juan Pedro Kusanovic,Tinnakorn Chaiworapongsa,Tinnakorn Chaiworapongsa,Ricardo Gomez,Jyh Kae Nien,Bo Hyun Yoon,Moshe Mazor,Jingqin Luo,David Banks,John A. Ryals,Chris Beecher +16 more
TL;DR: Among patients with spontaneous PTL with intact membranes, metabolic profiling of the amniotic fluid can be used to assess the risk of preterm delivery in the presence or absence of infection/inflammation.
Journal ArticleDOI
Parvovirus B19 infection in human pregnancy
Ronald F. Lamont,Ronald F. Lamont,Jack D. Sobel,Edi Vaisbuch,Edi Vaisbuch,Juan Pedro Kusanovic,Juan Pedro Kusanovic,Shali Mazaki-Tovi,Shali Mazaki-Tovi,Sun Kwon Kim,Niels Uldbjerg,Roberto Romero,Roberto Romero +12 more
TL;DR: This research highlights the need to understand more fully the immune response to Parvovirus B19 in women during pregnancy and how this infection affects the immune system during pregnancy.
Journal ArticleDOI
First-trimester maternal serum PP13 in the risk assessment for preeclampsia
Roberto Romero,Roberto Romero,Juan Pedro Kusanovic,Juan Pedro Kusanovic,Nandor Gabor Than,Nandor Gabor Than,Offer Erez,Francesca Gotsch,Jimmy Espinoza,Jimmy Espinoza,Samuel Edwin,Ilana Chefetz,Ricardo Gomez,Jyh Kae Nien,Marei Sammar,Beth L. Pineles,Sonia S. Hassan,Sonia S. Hassan,Hamutal Meiri,Yossi Tal,Ido Kuhnreich,Zoltán Papp,Howard Cuckle,Howard Cuckle +23 more
TL;DR: Maternal serum first-trimester PP13 appears to be a reasonable marker for risk assessment for preterm preeclampsia but a weak marker for severe preeclampia at term, and ineffective for identifying mild preeclamping at term.
Journal ArticleDOI
Characterization of the myometrial transcriptome and biological pathways of spontaneous human labor at term
Pooja Mittal,Roberto Romero,Roberto Romero,Adi L. Tarca,Adi L. Tarca,Juan M. Gonzalez,Juan M. Gonzalez,Sorin Draghici,Yi Xu,Zhong Dong,Chia Ling Nhan-Chang,Chia Ling Nhan-Chang,Tinnakorn Chaiworapongsa,Tinnakorn Chaiworapongsa,Stephen J. Lye,Juan Pedro Kusanovic,Juan Pedro Kusanovic,Leonard Lipovich,Shali Mazaki-Tovi,Shali Mazaki-Tovi,Sonia S. Hassan,Sonia S. Hassan,Sam Mesiano,Chong Jai Kim,Chong Jai Kim +24 more
TL;DR: Myometrium of women in spontaneous labor at term is characterized by a stereotypic gene expression pattern consistent with over-expression of the inflammatory response and leukocyte chemotaxis.