J
Judith C. Madden
Researcher at Liverpool John Moores University
Publications - 109
Citations - 3187
Judith C. Madden is an academic researcher from Liverpool John Moores University. The author has contributed to research in topics: Computer science & In silico. The author has an hindex of 30, co-authored 99 publications receiving 2576 citations. Previous affiliations of Judith C. Madden include Helmholtz Centre for Environmental Research - UFZ.
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Journal ArticleDOI
Measurement and estimation of electrophilic reactivity for predictive toxicology.
Johannes A.H. Schwöbel,Yana K. Koleva,Steven J. Enoch,Fania Bajot,Mark Hewitt,Judith C. Madden,David W. Roberts,Terry W Schultz,Mark T. D. Cronin +8 more
TL;DR: Measurement and Estimation of Electrophilic Reactivity for Predictive Toxicology Johannes A. H. Schw€obel, Yana K. Koleva, Steven J. Enoch, Fania Bajot, Mark Hewitt, Judith C.Madden, and Mark T. Schultz.
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Students' response to traditional and computer-assisted formative feedback: A comparative case study
TL;DR: It is concluded that electronic formative feedback can be returned more quickly and may be used to synthesise relevant feedback that is both fair and balanced.
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Assessing the exposure risk and impacts of pharmaceuticals in the environment on individuals and ecosystems
Kathryn E. Arnold,Alistair B.A. Boxall,A. Ross Brown,A. Ross Brown,Richard J. Cuthbert,Sally Gaw,Thomas H. Hutchinson,Susan Jobling,Judith C. Madden,Chris D. Metcalfe,Vinny Naidoo,Richard F. Shore,Judit E. G. Smits,Mark A. Taggart,Helen M. Thompson +14 more
TL;DR: It is concluded that an integration of diverse approaches is required to predict ‘unexpected’ risks; specifically, ecologically relevant, often long-term and non-lethal, consequences of pharmaceuticals in the environment for wildlife and ecosystems.
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Prediction of michael-type acceptor reactivity toward glutathione.
Johannes A.H. Schwöbel,Dominik Wondrousch,Yana K. Koleva,Judith C. Madden,Mark T. D. Cronin,Gerrit Schüürmann +5 more
TL;DR: A model has been developed to predict the kinetic rate constants (k(GSH) of α,β-unsaturated Michael acceptor compounds for their reaction with glutathione and has the potential to provide information to assist in the assessment and categorization of toxicants and in the application of integrated testing strategies.
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Identification of mechanisms of toxic action for skin sensitisation using a SMARTS pattern based approach
TL;DR: The ability to define a chemical's potential reaction mechanism is likely to be of significant benefit to regulators and risk assessors as it enables category formation and subsequent read-across to be performed.