Judith Magenheim

TL;DR: It is shown that long-chain fatty acids directly modulate the transcriptional activity of HNF-4α by binding as their acyl-CoA thioesters to the ligand-binding domain of H NF-4 α.

TL;DR: The tissue origins of cfDNA and thus the rate of death of specific cell types can be determined in humans, offering a minimally invasive window for diagnosing and monitoring a broad spectrum of human pathologies as well as providing a better understanding of normal tissue dynamics.

TL;DR: Deconvolution of cfDNA from patients reveals tissue contributions that agree with clinical findings in sepsis, islet transplantation, cancer of the colon, lung, breast and prostate, and cancer of unknown primary.

TL;DR: Deconvolution of cfDNA from patients reveals tissue contributions that agree with clinical findings in sepsis, islet transplantation, cancer of the colon, lung, breast and prostate, and cancer of unknown primary.

TL;DR: In this article, a large-scale pooled screening of SARS-CoV-2 infection is reported, where pooling strategies for RNA extraction and reverse transcription (RT)-PCR detection are proposed.