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Bryce Chackerian
Researcher at University of New Mexico
Publications - 108
Citations - 5892
Bryce Chackerian is an academic researcher from University of New Mexico. The author has contributed to research in topics: Epitope & Antigen. The author has an hindex of 34, co-authored 102 publications receiving 5291 citations. Previous affiliations of Bryce Chackerian include National Institutes of Health & Sandia National Laboratories.
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Journal ArticleDOI
The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers
Carlee E. Ashley,Carlee E. Ashley,Eric C. Carnes,Genevieve K Phillips,David Patrick Padilla,Paul N. Durfee,Page A. Brown,Tracey N. Hanna,Juewen Liu,Juewen Liu,Brandy Phillips,Mark B. Carter,Nick J. Carroll,Xingmao Jiang,Darren R. Dunphy,Cheryl L. Willman,Dimiter N. Petsev,Deborah G. Evans,Atul N. Parikh,Bryce Chackerian,Walker Wharton,David S. Peabody,C. Jeffrey Brinker +22 more
TL;DR: P porous nanoparticle-supported lipid bilayers (protocells) that synergistically combine properties of liposomes and nanoporous particles are reported that allow a single protocell loaded with a drug cocktail to kill a drug-resistant HCC cell, representing a 106-fold improvement over comparable liposome.
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Virus-like particles: flexible platforms for vaccine development
TL;DR: This review discusses the development of VLP-based platform technologies for vaccines against pathogens, as well as nontraditional targets such as self-antigens involved in chronic diseases.
Journal Article
High-Risk Human Papillomavirus Is Sexually Transmitted: Evidence from a Follow-Up Study of Virgins Starting Sexual Activity (Intercourse)
Susanne K. Kjaer,Bryce Chackerian,Adriaan J. C. van den Brule,Edith I. Svare,Gerson Paull,Jan M. M. Walbomers,John T. Schiller,Johannes E. Bock,Mark E. Sherman,Douglas R. Lowy,Chris L. J. M. Meijer +10 more
TL;DR: The results show that sexual intercourse is important in the transmission of HPV, and that HPV 16 VLP seroconversion and the development of cervical lesions only occur after HPV transmission, and no cervical lesions were found in HPV 16 DNA positive women who had seroconverted.
Journal ArticleDOI
Human immunodeficiency virus type 1 coreceptors participate in postentry stages in the virus replication cycle and function in simian immunodeficiency virus infection.
TL;DR: These studies suggest that there are interactions among the coreceptor, the viral envelope, and another viral gene product that govern postentry steps of virus replication that are consistent with the hypothesis that such interactions may be required for translocation of the virus core to the nucleus.
Journal ArticleDOI
Cell-Specific Delivery of Diverse Cargos by Bacteriophage MS2 Virus-Like Particles
Carlee Erin Ashley,Eric C. Carnes,Genevieve K Phillips,Paul N. Durfee,Mekensey Buley,Christopher A. Lino,David Patrick Padilla,Brandy Phillips,Mark B. Carter,Cheryl L. Willman,C. Jeffrey Brinker,Jerri C. Caldeira,Bryce Chackerian,Walker Wharton,David S. Peabody +14 more
TL;DR: The results demonstrate that MS2 VLPs, because of their tolerance of multivalent peptide display and their ability to specifically encapsidate a variety of chemically disparate cargos, induce selective cytotoxicity of cancer in vitro and represent a significant improvement in the characteristics of VLP-based delivery systems.