J
Julia Klein
Researcher at University of Toronto
Publications - 90
Citations - 3486
Julia Klein is an academic researcher from University of Toronto. The author has contributed to research in topics: Fentanyl & Pharmacokinetics. The author has an hindex of 32, co-authored 85 publications receiving 3362 citations. Previous affiliations of Julia Klein include University of Maryland, Baltimore & Toronto General Hospital.
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Journal ArticleDOI
Socio-economic disparities in preterm birth: causal pathways and mechanisms.
Michael S. Kramer,Lise Goulet,John E. Lydon,Louise Séguin,Helen McNamara,Clément Dassa,Robert W. Platt,Moy Fong Chen,Henriette Gauthier,Jacques Genest,Susan R. Kahn,Michael Libman,Rima Rozen,André Masse,Louise Miner,Guylaine Asselin,Alice Benjamin,Julia Klein,Gideon Koren +18 more
TL;DR: Improved understanding of the factors and processes that mediate social disparities in preterm birth should help not only in developing strategies to reduce the disparities but also in suggesting preventive interventions applicable across the entire socio-economic spectrum.
Journal ArticleDOI
A novel method using hair for determining hormonal levels in wildlife
TL;DR: Comparative tools for hormonal analysis provide insights into evolu-tionary theories based on behavioural aspects, such as productive suppression and the ‘challenge hypothesis’, and provides the resolution needed for studies of main behavioural trends, especially in stablehierarchical social systems.
Journal ArticleDOI
Comparison of oral iron chelator L1 and desferrioxamine in iron-loaded patients
Nancy F. Olivieri,Freedman Mh,Gideon Koren,Christine Hermann,Yedidia Bentur,Derrick Chung,Julia Klein,P. St. Louis,Douglas M. Templeton,Robert A. McClelland +9 more
TL;DR: Study in dogs and in volunteers showed no absorption of the L1-iron complex, excluding a contribution of absorption of intraluminal complexes of L1 and food iron to urinary iron excretion, and Pharmacokinetic studies showed an elimination half-life for L1 of 117-237 min.
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Systemic exposure to mercaptopurine as a prognostic factor in acute lymphocytic leukemia in children.
Gideon Koren,Gianmario Ferrazini,Hassan Sulh,Anne-Marie R Langevin,Joseph Kapelushnik,Julia Klein,Ester Giesbrecht,Stephen Soldin,Mark L. Greenberg +8 more
TL;DR: Low systemic exposure to oral mercaptopurine during maintenance therapy for acute lymphocytic leukemia in childhood adversely affects prognosis, and children should be studied at the beginning of maintenance therapy to establish the pharmacokinetics of merc laptopurine and the dose should be tailored to achieve an appropriate systemic exposure.
Journal ArticleDOI
A Randomized, Double-blind Comparison of Lumbar Epidural and Intravenous Fentanyl Infusions for Postthoracotomy Pain Relief: Analgesic, Pharmacokinetic, and Respiratory Effects
Alan N. Sandler,David Stringer,Larry Panos,Neal H. Badner,Mark Friedlander,Gideon Koren,Joel Katz,Julia Klein +7 more
TL;DR: Both groups demonstrated a similar degree of mild to moderate respiratory depression postoperatively, which was assessed with continuous respiratory inductance plethysmography and sequential arterial blood gas analysis.