J
Julia Szekeres-Bartho
Researcher at University of Pécs
Publications - 166
Citations - 7108
Julia Szekeres-Bartho is an academic researcher from University of Pécs. The author has contributed to research in topics: Pregnancy & Cytotoxic T cell. The author has an hindex of 49, co-authored 162 publications receiving 6490 citations. Previous affiliations of Julia Szekeres-Bartho include Hungarian Academy of Sciences.
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Journal ArticleDOI
A pivotal role for galectin-1 in fetomaternal tolerance
Sandra M. Blois,Juan M. Ilarregui,Mareike Tometten,Mariana Garcia,Arif S. Orsal,Rosalia Cordo-Russo,Marta A. Toscano,Germán A Bianco,Peter Kobelt,Bori Handjiski,Irene Tirado,Irene Tirado,Udo R. Markert,Burghard F. Klapp,Françoise Poirier,Julia Szekeres-Bartho,Gabriel A. Rabinovich,Gabriel A. Rabinovich,Petra C. Arck +18 more
TL;DR: It is shown that galectin-1 (Gal-1), an immunoregulatory glycan-binding protein, has a pivotal role in conferring fetomaternal tolerance and is a pivotal regulator of fetom maternal tolerance that has potential therapeutic implications in threatened pregnancies.
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A progesterone-dependent immunomodulatory protein alters the Th1 Th2 balance
TL;DR: The data indicate that the PIBF affects the Th1/Th2 balance, and via altered cytokine ratios it contributes to decreased cell-mediated responses during pregnancy.
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Immunological relationship between the mother and the fetus.
TL;DR: There is evidence now that immunological recognition of pregnancy is important for the maintenance of gestation, and that inadequate recognition of fetal antigens might result in failed pregnancy.
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Progesterone During Pregnancy: Endocrine–Immune Cross Talk in Mammalian Species and the Role of Stress
Petra C. Arck,Peter J. Hansen,Biserka Mulac Jericevic,Marie-Pierre Piccinni,Julia Szekeres-Bartho +4 more
TL;DR: Progesterone is critical for the establishment and the maintenance of pregnancy, both by its endocrine and immunological effects as mentioned in this paper, and it plays a role in uterine homing of NK cells and up-regulates HLA-G gene expression, the ligand for various NK inhibitory receptors.
Journal ArticleDOI
Progesterone as an immunomodulatory molecule
Julia Szekeres-Bartho,Aliz Barakonyi,Gabriella Pár,Beata Polgar,Tamas Palkovics,Laszlo Szereday +5 more
TL;DR: Progesterone binding results in the synthesis of a mediator protein named the progesterone-induced blocking factor (PIBF), which by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect.