J
Julian Taranda
Researcher at Cold Spring Harbor Laboratory
Publications - 9
Citations - 1223
Julian Taranda is an academic researcher from Cold Spring Harbor Laboratory. The author has contributed to research in topics: Basal ganglia & Striatum. The author has an hindex of 5, co-authored 9 publications receiving 938 citations.
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Journal ArticleDOI
Serial two-photon tomography for automated ex vivo mouse brain imaging
Timothy Ragan,Lolahon R. Kadiri,Kannan Umadevi Venkataraju,Karsten Bahlmann,Jason Sutin,Julian Taranda,Ignacio Arganda-Carreras,Yongsoo Kim,H. Sebastian Seung,Pavel Osten +9 more
TL;DR: An automated method is described that achieves high-throughput fluorescence imaging of mouse brains by integrating two-photon microscopy and tissue sectioning, which opens the door to routine systematic studies of neuroanatomy in mouse models of human brain disorders.
Journal ArticleDOI
Mapping Social Behavior-Induced Brain Activation at Cellular Resolution in the Mouse
Yongsoo Kim,Kannan Umadevi Venkataraju,Kith Pradhan,Carolin Mende,Julian Taranda,Srinivas C. Turaga,Ignacio Arganda-Carreras,Lydia Ng,Michael Hawrylycz,Kathleen S. Rockland,Kathleen S. Rockland,H. Sebastian Seung,Pavel Osten +12 more
TL;DR: In this paper, the authors apply an automated method for mapping brain activation in the mouse in order to probe how sex-specific social behaviors are represented in the male brain using the immediate-early-gene c-fos, a marker of neuronal activation, visualized by serial two-photon tomography.
Journal ArticleDOI
Mutant-IDH1-dependent chromatin state reprogramming, reversibility, and persistence
Sevin Turcan,Sevin Turcan,Vladimir Makarov,Julian Taranda,Yuxiang Wang,Armida W. M. Fabius,Armida W. M. Fabius,Wei Wu,Yupeng Zheng,Nour El-Amine,Sara Haddock,Sara Haddock,Gouri Nanjangud,H. Carl Lekaye,Cameron Brennan,Justin R. Cross,Jason T. Huse,Neil L. Kelleher,Pavel Osten,Craig B. Thompson,Timothy A. Chan,Timothy A. Chan +21 more
TL;DR: This study uses human astrocytes and glioma tumorspheres to generate an atlas of mutant-IDH1-induced epigenomic reprogramming and discovers genome-wide coordinate changes in the localization and intensity of multiple histone marks and chromatin states.
Journal ArticleDOI
Distinct Cortical-Thalamic-Striatal Circuits through the Parafascicular Nucleus.
Gil Mandelbaum,Julian Taranda,Trevor M. Haynes,Daniel Hochbaum,Daniel Hochbaum,Kee Wui Huang,Minsuk Hyun,Kannan Umadevi Venkataraju,Christoph Straub,Wengang Wang,Keiramarie Robertson,Pavel Osten,Bernardo L. Sabatini +12 more
TL;DR: In this paper, the thalamic parafascicular nucleus (PF) was found to have the highest density of striatum-projecting neurons among all sub-cortical structures.
Journal ArticleDOI
Central Control Circuit for Context-Dependent Micturition
Xun Helen Hou,Minsuk Hyun,Julian Taranda,Kee Wui Huang,Emmalee Todd,Danielle Feng,Emily Atwater,Donyell M Croney,Mark L. Zeidel,Pavel Osten,Bernardo L. Sabatini +10 more
TL;DR: It is demonstrated that a cluster of neurons expressing corticotropin-releasing hormone (Crh) in the pontine micturition center (PMC) is electrophysiologically distinct from their Crh-negative neighbors and sends glutamatergic projections to the spinal cord.