Julie F. Foley

TL;DR: Optimal fixation protocols for LCM analysis will facilitate the examination of gene expression in specific cell populations, accelerating investigations of the molecular differences responsible for the phenotypic changes observed during carcinogenesis.

TL;DR: Together, these data suggest that CYP2J2-derived metabolites are cardioprotective after ischemia, and the mechanism for thisCardioprotection involves activation of mitoKATP and p42/p44 MAPK.

TL;DR: It is concluded that CYP2J3 is one of the predominant enzymes responsible for the oxidation of endogenous arachidonic acid pools in rat heart myocytes and 11,12-epoxyeicosatrienoic acid may play an important functional role in the response of the heart to ischemia.

TL;DR: The data suggest that the majority of neoplasms in the lung begin as type II cell proliferations with progression to adenomas and carcinomas within the areas of hyperplasia and the lack of agreement between biochemical and morphological findings makes it difficult to hypothesize a cell of origin for the pulmonary neoplasm.

TL;DR: It is suggested that arsenic enhances development of skin neoplasias via the chronic stimulation of keratinocyte-derived growth factors and may be a rare example of a chemical carcinogen that acts as a co-promoter.