J
Julie King
Researcher at University of Nottingham
Publications - 148
Citations - 7235
Julie King is an academic researcher from University of Nottingham. The author has contributed to research in topics: Introgression & Social work. The author has an hindex of 36, co-authored 135 publications receiving 6573 citations. Previous affiliations of Julie King include IBM & Walter and Eliza Hall Institute of Medical Research.
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Journal ArticleDOI
The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor
David P. Gearing,Michael R. Comeau,Della Friend,Steven D. Gimpel,Catherine J. Thut,Jackie McGourty,Kelle K. Brasher,Julie King,Steven Gillis,Bruce Mosley,Steven F. Ziegler,David Cosman +11 more
TL;DR: A complementary DNA was isolated that encodes the high-affinity converting subunit of the LIF receptor, identical to the signal transducing sub unit of the IL-6 receptor, gp130, which confers high- Affinity binding of both LIF and OSM when expressed with the low-Affinity Lif receptor.
Journal ArticleDOI
Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor.
TL;DR: Two cDNA clones encoding a receptor for human granulocyte‐macrophage colony‐stimulating factor were isolated by expression screening of a library made from human placental mRNA and cross‐linking experiments revealed a similar size for the glycosylated receptors in transfected COS and haemopoietic cells.
Journal ArticleDOI
Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130.
David P. Gearing,C.J. Thut,T. VandeBos,S.D. Gimpel,P.B. Delaney,Julie King,V. Price,David Cosman,M.P. Beckmann +8 more
TL;DR: A cDNA clone encoding the human LIF receptor was isolated by expression screening of a human placental cDNA library and suggests a common signal transduction pathway for the two receptors and may help to explain similar biological effects of the two ligands.
Journal ArticleDOI
Molecular cloning and expression of cDNA encoding a murine myeloid leukaemia inhibitory factor (LIF).
David P. Gearing,Nicholas M. Gough,Julie King,D J Hilton,Nicos A. Nicola,Richard J. Simpson,Edouard C. Nice,Anne Kelso,D. Metcalf +8 more
TL;DR: Cloning, sequencing and expressing LIF has resolved several discrepancies in the literature concerning the identity of factors capable of inducing differentiation of murine myeloid leukaemic cells in vitro.
Journal ArticleDOI
Achieving yield gains in wheat.
Matthew P. Reynolds,John Foulkes,Robert T. Furbank,Simon Griffiths,Julie King,Erik H. Murchie,Martin A. J. Parry,Gustavo A. Slafer +7 more
TL;DR: Crop development should favour spike fertility to maximize harvest index so phenology must be tailored to different photoperiods, and sensitivity to unpredictable weather must be modulated to reduce conservative responses that reduce harvest index.