J
Julie M. Granka
Researcher at Stanford University
Publications - 24
Citations - 1396
Julie M. Granka is an academic researcher from Stanford University. The author has contributed to research in topics: Population & Biology. The author has an hindex of 13, co-authored 22 publications receiving 1175 citations. Previous affiliations of Julie M. Granka include Cornell University.
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Journal ArticleDOI
Hunter-gatherer genomic diversity suggests a southern African origin for modern humans
Brenna M. Henn,Christopher R. Gignoux,Matthew J. Jobin,Julie M. Granka,John Michael Macpherson,Jeffrey M. Kidd,Laura Rodríguez-Botigué,Sohini Ramachandran,Lawrence Hon,Abra Brisbin,Alice A. Lin,Peter A. Underhill,David Comas,Kenneth K. Kidd,Paul Norman,Peter Parham,Carlos Bustamante,Joanna L. Mountain,Marcus W. Feldman +18 more
TL;DR: It is found that African hunter-gatherer populations today remain highly differentiated, encompassing major components of variation that are not found in other African populations, and tend to have the lowest levels of genome-wide linkage disequilibrium among 27 African populations.
Journal ArticleDOI
Linkage Disequilibrium and Demographic History of Wild and Domestic Canids
Melissa M. Gray,Julie M. Granka,Carlos Bustamante,Nathan B. Sutter,Adam R. Boyko,Lan Zhu,Elaine A. Ostrander,Robert K. Wayne +7 more
TL;DR: In measuring LD and modeling demographic history under a composite-likelihood framework, it is found that two of five wild canid populations exhibit evidence of a historical population contraction and five domestic dog breeds display evidence for a minor population contraction during domestication and a more severe contraction during breed formation.
Journal ArticleDOI
An Unexpectedly Complex Architecture for Skin Pigmentation in Africans
Alicia R. Martin,Meng Lin,Julie M. Granka,Justin W Myrick,Xiaomin Liu,Alexandra Sockell,Elizabeth G. Atkinson,Cedric J. Werely,Marlo Möller,Manjinder S. Sandhu,David M. Kingsley,Eileen G. Hoal,Xiao Liu,Mark J. Daly,Mark J. Daly,Marcus W. Feldman,Christopher R. Gignoux,Carlos Bustamante,Brenna M. Henn +18 more
TL;DR: It is demonstrated that skin pigmentation is highly heritable, but known pigmentation loci explain only a small fraction of the variance, and how the architecture of skin Pigmentation can vary across humans subject to different local evolutionary pressures is shown.
Journal ArticleDOI
The Role of Selection in Shaping Diversity of Natural M. tuberculosis Populations
Caitlin S. Pepperell,Amanda M. Casto,Andrew Kitchen,Julie M. Granka,Omar E. Cornejo,Edward C. Holmes,Bruce W. Birren,James E. Galagan,James E. Galagan,Marcus W. Feldman +9 more
TL;DR: The results emphasize the parallel demographic histories of this obligate pathogen and its human host, and suggest that the dominant effect of selection on M.tb is removal of novel variants, with exceptions in an interesting group of genes involved in transportation and defense.
Journal ArticleDOI
Estimates of the Heritability of Human Longevity Are Substantially Inflated due to Assortative Mating
J. Graham Ruby,Kevin M. Wright,Kristin A. Rand,Amir R. Kermany,Keith Noto,Don Curtis,Neal Varner,Daniel Garrigan,Dmitri Slinkov,Ilya Dorfman,Julie M. Granka,Jake K. Byrnes,Natalie M. Myres,Catherine A. Ball +13 more
TL;DR: It is concluded that the true heritability of human longevity for birth cohorts across the 1800s and early 1900s was well below 10%, and that it has been generally overestimated due to the effect of assortative mating.