J
Julien E. Gautrot
Researcher at Queen Mary University of London
Publications - 121
Citations - 5483
Julien E. Gautrot is an academic researcher from Queen Mary University of London. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 30, co-authored 97 publications receiving 4475 citations. Previous affiliations of Julien E. Gautrot include Université de Montréal & University of Manchester.
Papers
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Journal ArticleDOI
Extracellular-matrix tethering regulates stem-cell fate
Britta Trappmann,Julien E. Gautrot,Julien E. Gautrot,John T. Connelly,John T. Connelly,Daniel G. T. Strange,Yuan Li,Michelle L. Oyen,Martien A. Cohen Stuart,Heike Boehm,Heike Boehm,Bojun Li,Viola Vogel,Joachim P. Spatz,Joachim P. Spatz,Fiona M. Watt,Wilhelm T. S. Huck,Wilhelm T. S. Huck +17 more
TL;DR: It is concluded that stem cells exert a mechanical force on collagen fibres and gauge the feedback to make cell-fate decisions, and are regulated by the elastic modulus of PAAm.
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Surface-Initiated Polymer Brushes in the Biomedical Field: Applications in Membrane Science, Biosensing, Cell Culture, Regenerative Medicine and Antibacterial Coatings
TL;DR: Surface-initiated polymer brushes in the biomedical field : applications in membrane science, biosensing, cell culture, regenerative medicine and antibacterial coatings.
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Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions
John T. Connelly,Julien E. Gautrot,Britta Trappmann,David W. M. Tan,Giacomo Donati,Wilhelm T. S. Huck,Wilhelm T. S. Huck,Fiona M. Watt +7 more
TL;DR: Micropatterned surfaces are employed to identify the signalling pathways by which restricted ECM contact triggers human epidermal stem cells to initiate terminal differentiation and demonstrate how biophysical cues are transduced into transcriptional responses that determine epidersmal cell fate.
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Polymer Brushes Showing Non‐Fouling in Blood Plasma Challenge the Currently Accepted Design of Protein Resistant Surfaces
Cesar Rodriguez-Emmenegger,Cesar Rodriguez-Emmenegger,Eduard Brynda,Tomáš Riedel,Milan Houska,Vladimir Subr,Aldo Bologna Alles,Erol Hasan,Julien E. Gautrot,Wilhelm T. S. Huck,Wilhelm T. S. Huck +10 more
TL;DR: The level of blood plasma fouling was below the detection limit of surface plasmon resonance (SPR) despite being a hydrogen bond donor and displaying a moderate wettability, thus challenging the currently accepted views for the design of antifouling properties.
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Cell sensing of physical properties at the nanoscale: Mechanisms and control of cell adhesion and phenotype
TL;DR: This review presents some of the important molecular mechanisms underlying cell adhesion to biomaterials mediated by integrins and discusses the nanoscale engineered platforms used to control these processes.