J
Jumei Shi
Researcher at Tongji University
Publications - 70
Citations - 1654
Jumei Shi is an academic researcher from Tongji University. The author has contributed to research in topics: Apoptosis & Cell growth. The author has an hindex of 16, co-authored 70 publications receiving 1314 citations. Previous affiliations of Jumei Shi include Anhui Medical University.
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Journal ArticleDOI
Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma
Lu Jiang,Zhaohui Gu,Zi-Xun Yan,Xia Zhao,Yin-Yin Xie,Zi-Guan Zhang,Chun-Ming Pan,Yuan Hu,Chang-Ping Cai,Ying Dong,Jinyan Huang,Li Wang,Yang Shen,Guoyu Meng,Jianfeng Zhou,Jianda Hu,Jin-Fen Wang,Yuan-Hua Liu,Lin-Hua Yang,Feng Zhang,Jianmin Wang,Zhao Wang,Zhigang Peng,Fang-Yuan Chen,Zi-Min Sun,Hao Ding,Jumei Shi,Jian Hou,Jin-Song Yan,Jing-Yi Shi,Lan Xu,Yang Li,Jing Lu,Zhong Zheng,Wen Xue,Wei-Li Zhao,Zhu Chen,Sai-Juan Chen +37 more
TL;DR: This work identified somatic gene mutations in 25 people with NKTCL by whole-exome sequencing and confirmed them in an extended validation group of 80 people by targeted sequencing, contributing to the understanding of the disease mechanism ofNKTCL.
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Combinatorial efficacy of anti-CS1 monoclonal antibody elotuzumab (HuLuc63) and bortezomib against multiple myeloma.
Frits van Rhee,Susann Szmania,Myles B.C. Dillon,Anne van Abbema,Xin Li,Mary K. Stone,Tarun K. Garg,Jumei Shi,Amberly Moreno-Bost,Rui Yun,Balaji Balasa,Bishwa Ganguly,Debra Chao,Audie Rice,Fenghuang Zhan,John D. Shaughnessy,Bart Barlogie,Shmuel Yaccoby,Daniel E. H. Afar +18 more
TL;DR: It is shown that elotuzumab could induce patient-derived myeloma cell killing within the bone marrow microenvironment using a SCID-hu mouse model and that CS1 gene and cell surface protein expression persisted on myelomas collected after bortezomib administration.
Journal ArticleDOI
Bortezomib down-regulates the cell surface expression of HLA-class I and enhances natural killer cell-mediated lysis of myeloma
Jumei Shi,Guido Tricot,Tarun K. Garg,Priyangi A. Malaviarachchi,Susann Szmania,Rachel E. Kellum,Brian Storrie,Arend Mulder,John D. Shaughnessy,Bart Barlogie,Frits van Rhee +10 more
TL;DR: In this paper, Bortezomib significantly enhances the sensitivity of multiple myeloma (MM) to allogeneic and autologous NK cell-mediated lysis, and the level of decrease in class I expression correlates with increased susceptibility to lysis by NK cells.
Journal ArticleDOI
Decreased Ferroportin Promotes Myeloma Cell Growth and Osteoclast Differentiation
Zhimin Gu,He Wang,Jiliang Xia,Ye Yang,Zhendong Jin,Hongwei Xu,Jumei Shi,Ivana De Domenico,Guido Tricot,Fenghuang Zhan +9 more
TL;DR: It is demonstrated that downregulation of FPN1 plays critical roles in promoting myeloma cell growth and bone resorption in multipleMyeloma.
Journal ArticleDOI
Multiple myeloma cancer stem cells
TL;DR: The current state of knowledge of MMSC regarding their phenotype, mechanisms of drug resistance, signaling pathways that regulate MMSCs self-renewal and differentiation, abnormal microRNAs expression, and their interactions with the BM microenvironment are summarized.