Jianda Hu

TL;DR: There is a need to (1) lower the prices of cancer drugs to allow more patients to afford them and (2) maintain sound long-term health care policies.

TL;DR: This work identified somatic gene mutations in 25 people with NKTCL by whole-exome sequencing and confirmed them in an extended validation group of 80 people by targeted sequencing, contributing to the understanding of the disease mechanism ofNKTCL.

TL;DR: Adult patients with B- cell acute lymphoblastic leukemia had more cooperative mutations and greater enrichment for alterations of epigenetic modifiers and genes linked to B-cell development, suggesting difference in the target cells of transformation between adult and pediatric patients and may explain in part the disparity in their responses to treatment.

TL;DR: Sintilimab could be a new treatment option for patients with relapsed or refractory classical Hodgkin lymphoma in China and is registered with ClinicalTrials.gov, number NCT03114683.

TL;DR: These results demonstrate high and durable ORR and CR rates in patients with relapsed/refractory MCL and Zanubrutinib was generally well tolerated; grade ≥3 BTK inhibitor-associated toxicities were uncommon.