J
Jun Sukegawa
Researcher at University of Tokyo
Publications - 12
Citations - 697
Jun Sukegawa is an academic researcher from University of Tokyo. The author has contributed to research in topics: Gene & Complementary DNA. The author has an hindex of 8, co-authored 11 publications receiving 681 citations.
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Journal ArticleDOI
The yes-related cellular gene lyn encodes a possible tyrosine kinase similar to p56lck.
Yuji Yamanashi,Shinichi Fukushige,Kentaro Semba,Jun Sukegawa,Nobuyuki Miyajima,K. Matsubara,Tadashi Yamamoto,Kumao Toyoshima +7 more
TL;DR: With v-yes DNA as the probe, a human cDNA library made from placental RNA was screened under relaxed conditions, and DNA clones derived from a novel genetic locus, termed lyn, were obtained and showed that the lyn gene is located on human chromosome 8 q13-qter.
Journal ArticleDOI
yes-related protooncogene, syn, belongs to the protein-tyrosine kinase family
Kentaro Semba,Makoto Nishizawa,Nobuyuki Miyajima,Michihiro C. Yoshida,Jun Sukegawa,Yuji Yamanashi,Motomichi Sasaki,Tadashi Yamamoto,Kumao Toyoshima +8 more
TL;DR: Results show that syn is a new member of the tyrosine kinase oncogene family.
Journal ArticleDOI
Characterization of cDNA clones for the human c-yes gene.
Jun Sukegawa,Kentaro Semba,Yuji Yamanashi,Makoto Nishizawa,Nobuyuki Miyajima,Tadashi Yamamoto,Kumao Toyoshima +6 more
TL;DR: Three c-yes cDNA clones obtained from poly(A)+ RNA of human embryo fibroblasts showed that they contained inserts corresponding to nearly full-length human c- yes mRNA, which could encode a polypeptide of 543 amino acids with a relative molecular weight (Mr) of 60,801.
Journal ArticleDOI
Location of the c-yes Gene on the Human Chromosome and its Expression in Various Tissues
Kentaro Semba,Yuji Yamanashi,Makoto Nishizawa,Jun Sukegawa,Michihiro C. Yoshida,Motomichi Sasaki,Tadashi Yamamoto,Kumao Toyoshima +7 more
TL;DR: Analysis of DNA from human embryo fibroblasts showed that ten Eco RI fragments were hybridizable with the Yamaguchi sarcoma virus oncogene (v-yes), and there was evidence for multiple copies of yes-related genes in the human genome.
Journal ArticleDOI
Human liver type pyruvate kinase: cDNA cloning and chromosomal assignment.
Kenzaburo Tani,Fujii H,Hisashi Tsutsumi,Jun Sukegawa,Kumao Toyoshima,Michihiro C. Yoshida,Tamio Noguchi,Takehiko Tanaka,Shiro Miwa +8 more
TL;DR: Comparisons of the sequence data with the rat PK cDNAs indicated that the cDNA encoded information for the carboxyl terminal 105 amino acids of a human L-type PK and a 3' untranslated region of 734 nucleotides.