Y
Yuji Yamanashi
Researcher at University of Tokyo
Publications - 88
Citations - 6511
Yuji Yamanashi is an academic researcher from University of Tokyo. The author has contributed to research in topics: Neuromuscular junction & LYN. The author has an hindex of 41, co-authored 85 publications receiving 6157 citations. Previous affiliations of Yuji Yamanashi include Tokyo Medical and Dental University.
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Journal ArticleDOI
Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice
Hirofumi Nishizumi,Ichiro Taniuchi,Yuji Yamanashi,Daisuke Kitamura,Dusko Ilic,Shigeo Mori,Takeshi Watanabe,Tadashi Yamamoto +7 more
TL;DR: It is concluded that Lyn plays a role in signal transduction for not only clonal expansion and terminal differentiation of peripheral B cells but also elimination of autoreactive B cells.
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Association of B cell antigen receptor with protein tyrosine kinase Lyn
TL;DR: The Lyn protein and its kinase activity could be coimmunoprecipitated with IgM from detergent lysates and is suggested to participate in antigen-mediated signal transduction.
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Autoantibodies to low-density lipoprotein receptor-related protein 4 in myasthenia gravis.
TL;DR: It is shown that a proportion of AChR antibody‐negative patients have autoantibodies to Lrp4, which indicates the involvement of L rp4 antibodies in the pathogenesis of A ChR antibody-negative MG.
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The muscle protein Dok-7 is essential for neuromuscular synaptogenesis.
Kumiko Okada,Akane Inoue,Momoko Okada,Yoji Murata,Shigeru Kakuta,Takafumi Jigami,Sachiko Kubo,Hirokazu Shiraishi,Katsumi Eguchi,Masakatsu Motomura,Tetsu Akiyama,Yoichiro Iwakura,Osamu Higuchi,Yuji Yamanashi +13 more
TL;DR: The formation of the neuromuscular synapse requires muscle-specific receptor kinase (MuSK) to orchestrate postsynaptic differentiation, including the clustering of receptors for the neurotransmitter acetylcholine.
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Construction of an Excisable Bacterial Artificial Chromosome Containing a Full-Length Infectious Clone of Herpes Simplex Virus Type 1: Viruses Reconstituted from the Clone Exhibit Wild-Type Properties In Vitro and In Vivo
TL;DR: The infectious molecular clone pYEbac102 is in fact useful for mutagenesis of the HSV-1 genome by bacterial genetics, and a recombinant virus carrying amino acid substitutions in both copies of the α0 gene was generated.