J
Jun Uno
Researcher at Chiba University
Publications - 48
Citations - 1292
Jun Uno is an academic researcher from Chiba University. The author has contributed to research in topics: Candida albicans & Gene. The author has an hindex of 17, co-authored 48 publications receiving 1197 citations. Previous affiliations of Jun Uno include Toho University.
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Journal ArticleDOI
C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia
Sho Yamasaki,Makoto Matsumoto,Osamu Takeuchi,Tetsuhiro Matsuzawa,Eri Ishikawa,Machie Sakuma,Hiroaki Tateno,Jun Uno,Jun Hirabayashi,Yuzuru Mikami,Kiyoshi Takeda,Shizuo Akira,Takashi Saito +12 more
TL;DR: Results indicate that Mincle is the first specific receptor for Malassezia species to be reported and plays a crucial role in immune responses to this fungus.
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In Vitro Antifungal Activity of Micafungin (FK463) against Dimorphic Fungi: Comparison of Yeast-Like and Mycelial Forms
TL;DR: The results of this study suggest that the growth form employed in antifungal susceptibility testing of dimorphic fungi can considerably influence the interpretation of results, and warrant further investigations of micafungin as a therapeutic agent for infections caused by dimorphics fungi.
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Development of a highly efficient gene targeting system induced by transient repression of YKU80 expression in Candida glabrata
TL;DR: A new system whereby the expression of YKU80 was restored following a transient knockdown of expression during transformation, and the levels of mRNA transcription were restored and no difference in the survival ratio in vivo compared to that with the YK U80 wild-type strain was identified.
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Intestinal Resident Yeast Candida glabrata Requires Cyb2p-Mediated Lactate Assimilation to Adapt in Mouse Intestine
Keigo Ueno,Keigo Ueno,Yasuhiko Matsumoto,Jun Uno,Kaname Sasamoto,Kazuhisa Sekimizu,Yuki Kinjo,Hiroji Chibana +7 more
TL;DR: In this article, the authors describe the C. glabrata CYB2 gene encoding lactate dehydrogenase as an adaptation factor for survival in the intestine and conclude that CYb2p-mediated lactate assimilation is necessary for proliferation in the intestinal tract, as the intestine is rich in lactate produced by bacteria flora but not glucose.
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Pathogenicity and virulence of Candida dubliniensis: comparison with C. albicans.
Maria Marluce dos Santos Vilela,Katsuhiko Kamei,Ayako Sano,Reiko Tanaka,Jun Uno,I. Takahashi,J. Ito,Kyoko Yarita,M. Miyaji +8 more
TL;DR: Results clearly indicated that C. dubliniensis is less virulence than C. albicans, a newly described fungus that is frequently isolated from the oral cavities of HIV-positive patients.