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Jun Uno

Researcher at Chiba University

Publications -  48
Citations -  1292

Jun Uno is an academic researcher from Chiba University. The author has contributed to research in topics: Candida albicans & Gene. The author has an hindex of 17, co-authored 48 publications receiving 1197 citations. Previous affiliations of Jun Uno include Toho University.

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In Vitro Antifungal Activity of Micafungin (FK463) against Dimorphic Fungi: Comparison of Yeast-Like and Mycelial Forms

TL;DR: The results of this study suggest that the growth form employed in antifungal susceptibility testing of dimorphic fungi can considerably influence the interpretation of results, and warrant further investigations of micafungin as a therapeutic agent for infections caused by dimorphics fungi.
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Development of a highly efficient gene targeting system induced by transient repression of YKU80 expression in Candida glabrata

TL;DR: A new system whereby the expression of YKU80 was restored following a transient knockdown of expression during transformation, and the levels of mRNA transcription were restored and no difference in the survival ratio in vivo compared to that with the YK U80 wild-type strain was identified.
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Intestinal Resident Yeast Candida glabrata Requires Cyb2p-Mediated Lactate Assimilation to Adapt in Mouse Intestine

TL;DR: In this article, the authors describe the C. glabrata CYB2 gene encoding lactate dehydrogenase as an adaptation factor for survival in the intestine and conclude that CYb2p-mediated lactate assimilation is necessary for proliferation in the intestinal tract, as the intestine is rich in lactate produced by bacteria flora but not glucose.
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Pathogenicity and virulence of Candida dubliniensis: comparison with C. albicans.

TL;DR: Results clearly indicated that C. dubliniensis is less virulence than C. albicans, a newly described fungus that is frequently isolated from the oral cavities of HIV-positive patients.