J
Junho Lee
Researcher at Seoul National University
Publications - 215
Citations - 11057
Junho Lee is an academic researcher from Seoul National University. The author has contributed to research in topics: Caenorhabditis elegans & Gene. The author has an hindex of 33, co-authored 176 publications receiving 9695 citations. Previous affiliations of Junho Lee include Yonsei University & California Institute of Technology.
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Journal ArticleDOI
Calreticulin, a calcium-binding molecular chaperone, is required for stress response and fertility in Caenorhabditis elegans.
Byung-Jae Park,Dukgyu Lee,Jae-Ran Yu,Sunki Jung,Kyu-Yeong Choi,Jungsoo Lee,Jiyeon Lee,Yun Sik Kim,Jin I. Lee,Jae Young Kwon,Junho Lee,Andrew Singson,Woo Keun Song,Soo Hyun Eom,Chul-Seung Park,Do Han Kim,Jaya Bandyopadhyay,Joohong Ahnn +17 more
TL;DR: The functional characterization of Caenorhabditis elegans calreticulin (crt-1) is reported, suggesting that CRT-1 may be important for stress-induced chaperoning function in C. elegans.
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unc-101, a gene required for many aspects of Caenorhabditis elegans development and behavior, encodes a clathrin-associated protein.
TL;DR: Cloned unc-101 is cloned and found that it encodes a homolog of the mammalian medium chains of clathrin-associated protein complexes located at the trans-Golgi and the plasma membrane, AP47 and AP50, respectively, which might contribute to the negative regulation of vulval differentiation.
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The Genetic Basis of Natural Variation in Caenorhabditis elegans Telomere Length.
Daniel E. Cook,Stefan Zdraljevic,Robyn E. Tanny,Beom-Seok Seo,David D. Riccardi,Luke M. Noble,Matthew V. Rockman,Mark J. Alkema,Christian Braendle,Jan E. Kammenga,John Wang,Leonid Kruglyak,Marie-Anne Félix,Junho Lee,Erik C. Andersen +14 more
TL;DR: It is found that telomere-length variation does not correlate with offspring production or longevity in C. elegans wild isolates, suggesting that naturally long telomeres play a limited role in modifying fitness phenotypes in Cournorhabditis elegans.
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Ethanol-response genes and their regulation analyzed by a microarray and comparative genomic approach in the nematode Caenorhabditis elegans.
Jae Young Kwon,Mingi Hong,Min Sung Choi,Sujin Kang,Kyle Duke,Stuart K. Kim,Sunho Lee,Junho Lee +7 more
TL;DR: The nematode Caenorhabditis elegans is used as a model system to identify and characterize the genes that are affected by ethanol exposure and to link those genes functionally into an ethanol-induced gene network.
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ARK-1 Inhibits EGFR Signaling in C. elegans
TL;DR: A screen for synthetic enhancers of sli-1 identified ark-1 (forAck-related tyrosine kinase), a novel inhibitor of let-23 EGFR signaling in C. elegans, which suggests that ARK-1 acts upstream of RAS and is dependent upon SEM-5.