Junle Qu

TL;DR: It is demonstrated that rGO/MTX/SB combined with laser irradiation provided a synergistic chemo-immuno-photothermal effect against tumors by in situ vaccination and inhibition of immunosuppressive microenvironment.

TL;DR: This study developed an enhanced squaraine variant dye (MitoESq-635) to study the dynamic structures of mitochondrial cristae in live cells with a superresolution technique, demonstrating the emerging capability of optical STED nanoscopy to investigate intracellular physiological processes with nanoscale resolution for an extended period of time.

TL;DR: A BODIPY-arsenicate conjugate 1-based fluorescent molecular rotor was designed to covalently bind vicinal dithiol-containing proteins in the ER, exhibiting a bifunction of reticulophagy initiation and microviscosity evaluation.

TL;DR: The nontoxic probe Tyro-1 provides information about H2O2-mediated upregulation of tyrosinase through Cellular imaging through cellular imaging, and its two-photon imaging ability makes it a noninvasive tool for validating the expression of tyosinase in the live cells.

TL;DR: A phasor plot approach combined with fluorescence lifetime imaging microscopy (FLIM) is used to resolve the problem of stimulated emission partially inhibiting the spontaneous emission in the periphery of a diffraction-limited area, providing a 86 nm higher resolution than that in traditional STED imaging at a depletion power of 20 mW.