J
Jürgen Eckel
Researcher at University of Düsseldorf
Publications - 156
Citations - 8992
Jürgen Eckel is an academic researcher from University of Düsseldorf. The author has contributed to research in topics: Insulin & Insulin resistance. The author has an hindex of 50, co-authored 156 publications receiving 8137 citations. Previous affiliations of Jürgen Eckel include Pierre-and-Marie-Curie University & University of Palermo.
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Journal ArticleDOI
Chemerin is a novel adipocyte-derived factor inducing insulin resistance in primary human skeletal muscle cells.
Henrike Sell,Jurga Laurencikiene,Annika Taube,Kristin Eckardt,A Cramer,A Horrighs,Peter Arner,Jürgen Eckel +7 more
TL;DR: Adipocyte-derived secretion of chemerin may be involved in the negative cross talk between adipose tissue and skeletal muscle contributing to the negative relationship between obesity and insulin sensitivity.
Journal ArticleDOI
Sleep, sleep-disordered breathing and metabolic consequences
TL;DR: The relative role of obesity and OSA in the pathogenesis of metabolic alterations is still unclear and is intensively studied in clinical and experimental models.
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Risk of diabetes-associated diseases in subgroups of patients with recent-onset diabetes: a 5-year follow-up study.
Oana P. Zaharia,Klaus Strassburger,Alexander Strom,Gidon J. Bönhof,Yanislava Karusheva,Sofia Antoniou,Kálmán Bódis,D Markgraf,Volker Burkart,Karsten Müssig,Jong-Hee Hwang,Olof Asplund,Leif Groop,Emma Ahlqvist,Jochen Seissler,Peter P. Nawroth,Stefan Kopf,Sebastian M. Schmid,Michael Stumvoll,Andreas Pfeiffer,Stefan Kabisch,Sergey Tselmin,Hans U. Häring,Dan Ziegler,Oliver Kuss,Julia Szendroedi,Michael Roden,Bengt-Frederik Belgardt,Anette E. Buyken,Jürgen Eckel,Gerd Geerling,Hadi Al-Hasani,Christian Herder,Andrea Icks,Jorg Kotzka,Eckart Lammert,Daniel F. Markgraf,Wolfgang Rathmann +37 more
TL;DR: In patients with newly diagnosed type 1 or type 2 diabetes, hepatocellular lipid content was highest at baseline in patients assigned to the SIRD cluster and insulin resistance index at baseline was highest in patients with SIRD and MOD.
Journal ArticleDOI
Adipo-Myokines: Two Sides of the Same Coin—Mediators of Inflammation and Mediators of Exercise
Silja Raschke,Jürgen Eckel +1 more
TL;DR: This review summarizes the current literature regarding the most discussed contraction-regulated moykines like IL-6, IL-15, irisin, BDNF, ANGPTL4, FGF21, myonectin and MCP-1 and tries to elaborate on the question why pro-inflammatory adipokines on the one hand are upregulated in the obese state, and have beneficial effects after exercise on the other hand.
Journal ArticleDOI
Effects of tumour necrosis factor alpha (TNFα) on glucose transport and lipid metabolism of newly-differentiated human fat cells in cell culture
TL;DR: The data suggest that TNFα induces a catabolic state in human adipose tissue which includes a loss of the stimulatory effect of insulin on glucose transport and may contribute to the loss of adipOSE tissue observed during cachexia in man.