Jyh-Ping Hsu

TL;DR: In this paper, the effect of the local liquid permittivity surrounding the DNA nanoparticle, referred to as the local permittivities environment (LPE) effect, on its electrokinetic translocation through a nanopore is investigated for the first time using a continuum-based model, composed of the coupled Poisson-Nernst-Planck (PNP) equations for the ionic mass transport and the Stokes and Brinkman equations for hydrodynamic fields in the region outside of the DNA and within the ion-penetrable layer of the nanoparticle

TL;DR: It is shown that, in general, the surface potential of a polyelectrolyte increases nonlinearly with its surface charge; a linear relation exists between them, however, when the latter is sufficiently small; and the more dilute the concentration of polyElectrolytes, the broader the range in which they are linearly correlated.

TL;DR: It is shown that manipulation of surface charge can occur without changing pH of the background electrolyte, which is especially important for applications where maintaining pH at a constant and physiological level is necessary.

TL;DR: It is shown that the CCC ratio of counterions is a complicated function of the valences of the ion species in the liquid phase and the sizes of particles, depending upon the thickness of the Debye length.

TL;DR: The results of numerical simulation reveal that if both particle and pore are positively charged, the variation of the mobility of a particle may have a local minimum as the thickness of the double layer varies, which is not reported in the literature.