K
K. F. Rabe
Researcher at Leiden University Medical Center
Publications - 49
Citations - 2431
K. F. Rabe is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Asthma & Medicine. The author has an hindex of 17, co-authored 35 publications receiving 2239 citations.
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Journal ArticleDOI
The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma
B Abraham,Josep M. Antó,Esther Barreiro,Ehd Bel,Giovanni Bonsignore,Jean Bousquet,J. Castellsagué,Pascal Chanez,Fabio Cibella,Giuseppina Cuttitta,B. Dahlén,SE Dahlen,N Drews,Ratko Djukanovic,Leonardo M. Fabbri,Gert Folkerts,Mina Gaga,Christina Gratziou,G Guerrera,S. T. Holgate,P H Howarth,Sebastian L. Johnston,F. Kanniess,Johan Kips,Huib A. M. Kerstjens,Maria Kumlin,H. Magnussen,Frans P. Nijkamp,N. Papageorgiou,Alberto Papi,Dirkje S. Postma,Romain Pauwels,K. F. Rabe,K Richter,AC Roldaan,Micaela Romagnoli,A. Roquet,C Sanjuas,NM Siafakas,Wim Timens,Nikolaos Tzanakis,Vachier,A. M. Vignola,Louise Watson,G Yourgioti,Enfumosa Study Grp +45 more
TL;DR: It is suggested that severe asthma might be a different form of asthma rather than an increase in asthma symptoms, and longitudinal studies and interventions are needed to define the mechanisms in severe asthma.
Journal ArticleDOI
Risk factors of frequent exacerbations in difficult-to-treat asthma
ten A. Brinke,P. J. Sterk,Ad A.M. Masclee,Ph. Spinhoven,J.T. Schmidt,A. H. Zwinderman,K. F. Rabe,Elisabeth H. Bel +7 more
TL;DR: The results show that recurrent exacerbations in asthma are associated with specific co-morbid factors that are easy to detect and that are treatable and Therapeutic interventions aimed at correcting these factors are likely to reduce morbidity and medical expenditure in patients with asthma.
Journal ArticleDOI
Airway inflammation in obese and nonobese patients with difficult-to-treat asthma
TL;DR: The aim of this study was to investigate the relationship between obesity (body mass index) and factors related with asthma severity in patients with difficult‐to‐treat asthma.
Journal ArticleDOI
Prioritised research agenda for prevention and control of chronic respiratory diseases
Jean Bousquet,James P. Kiley,Eric D. Bateman,Giovanni Viegi,Alvaro A. Cruz,N. Khaltaev,N. Ait Khaled,Carlos E. Baena-Cagnani,Mauricio Lima Barreto,Nils E. Billo,Giorgio Walter Canonica,K-H. Carlsen,Niels H. Chavannes,A.G. Chuchalin,Jeffrey M. Drazen,Leonardo M. Fabbri,Margaret W. Gerbase,Marc Humbert,Guy Joos,Mohammad Reza Masjedi,S. Makino,K. F. Rabe,Teresa To,L. Zhi +23 more
TL;DR: A prioritised research agenda should encapsulate all of these considerations in the frame of the global fight against NCDs, which requires both CRD-targeted interventions and transverse NCD programmes which include CRDs.
Journal ArticleDOI
Alveolar nitric oxide versus measures of peripheral airway dysfunction in severe asthma
TL;DR: It is concluded that alveolar nitric oxide is closely related to parameters of peripheral airway dysfunction in patients with severe asthma, and that oral steroid-dependent asthmatics have more peripheralAirway disease than nonsteroid-dependentAsthma patients on chronic oral steroid treatment have more extensive disease and require additional anti-inflammatory treatment to better target the peripheral airways.