F
Frans P. Nijkamp
Researcher at Utrecht University
Publications - 391
Citations - 14280
Frans P. Nijkamp is an academic researcher from Utrecht University. The author has contributed to research in topics: Histamine & Immunoglobulin E. The author has an hindex of 64, co-authored 391 publications receiving 13902 citations. Previous affiliations of Frans P. Nijkamp include University of Giessen & Chulalongkorn University.
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Journal ArticleDOI
The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma
B Abraham,Josep M. Antó,Esther Barreiro,Ehd Bel,Giovanni Bonsignore,Jean Bousquet,J. Castellsagué,Pascal Chanez,Fabio Cibella,Giuseppina Cuttitta,B. Dahlén,SE Dahlen,N Drews,Ratko Djukanovic,Leonardo M. Fabbri,Gert Folkerts,Mina Gaga,Christina Gratziou,G Guerrera,S. T. Holgate,P H Howarth,Sebastian L. Johnston,F. Kanniess,Johan Kips,Huib A. M. Kerstjens,Maria Kumlin,H. Magnussen,Frans P. Nijkamp,N. Papageorgiou,Alberto Papi,Dirkje S. Postma,Romain Pauwels,K. F. Rabe,K Richter,AC Roldaan,Micaela Romagnoli,A. Roquet,C Sanjuas,NM Siafakas,Wim Timens,Nikolaos Tzanakis,Vachier,A. M. Vignola,Louise Watson,G Yourgioti,Enfumosa Study Grp +45 more
TL;DR: It is suggested that severe asthma might be a different form of asthma rather than an increase in asthma symptoms, and longitudinal studies and interventions are needed to define the mechanisms in severe asthma.
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A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation.
Nathaniel M. Weathington,Anneke H. van Houwelingen,Brett D. Noerager,Patricia L. Jackson,Aletta D. Kraneveld,F. Shawn Galin,Gert Folkerts,Frans P. Nijkamp,J. Edwin Blalock +8 more
TL;DR: PGP's activity links degradation of ECM with neutrophil recruitment in airway inflammation, and PGP may be a biomarker and therapeutic target for neutrophilic inflammatory diseases.
Journal ArticleDOI
Phospholipase A2 activity of guinea-pig isolated perfused lungs: stimulation, and inhibition by anti-inflammatory steroids.
TL;DR: It is suggested that agents which liberate prostaglandin endoperoxides and thromboxane A2 from perfused lungs do so by activating phospholipase A2.
Journal ArticleDOI
Reactive oxygen species as mediators in asthma.
TL;DR: With the use of inhibitors, transgenic animals and measurements of the release of ROS within the airways, it became clear that oxidative stress contributes to the initiation and worsening of inflammatory respiratory disorders.