H
Huib A. M. Kerstjens
Researcher at University Medical Center Groningen
Publications - 437
Citations - 18893
Huib A. M. Kerstjens is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: COPD & Asthma. The author has an hindex of 62, co-authored 398 publications receiving 16798 citations. Previous affiliations of Huib A. M. Kerstjens include University of Groningen & University of Twente.
Papers
More filters
Journal ArticleDOI
An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice.
Helen K. Reddel,D. Robin Taylor,Eric D. Bateman,Louis-Philippe Boulet,Homer A. Boushey,William W. Busse,Thomas B. Casale,Pascal Chanez,Paul L. Enright,Peter G. Gibson,Johan C. de Jongste,Huib A. M. Kerstjens,Stephen C. Lazarus,Mark L Levy,Paul M. O'Byrne,Martyn R Partridge,Ian D. Pavord,Malcolm R. Sears,Peter J. Sterk,Stuart W. Stoloff,Sean D. Sullivan,Stanley J. Szefler,Mike Thomas,Sally E. Wenzel +23 more
TL;DR: New definitions for asthma control, severity, and exacerbations are developed, based on current treatment principles and clinical and research relevance, to provide a basis for a multicomponent assessment of asthma by clinicians, researchers, and other relevant groups in the design, conduct, and evaluation of clinical trials, and in clinical practice.
Journal ArticleDOI
The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma
B Abraham,Josep M. Antó,Esther Barreiro,Ehd Bel,Giovanni Bonsignore,Jean Bousquet,J. Castellsagué,Pascal Chanez,Fabio Cibella,Giuseppina Cuttitta,B. Dahlén,SE Dahlen,N Drews,Ratko Djukanovic,Leonardo M. Fabbri,Gert Folkerts,Mina Gaga,Christina Gratziou,G Guerrera,S. T. Holgate,P H Howarth,Sebastian L. Johnston,F. Kanniess,Johan Kips,Huib A. M. Kerstjens,Maria Kumlin,H. Magnussen,Frans P. Nijkamp,N. Papageorgiou,Alberto Papi,Dirkje S. Postma,Romain Pauwels,K. F. Rabe,K Richter,AC Roldaan,Micaela Romagnoli,A. Roquet,C Sanjuas,NM Siafakas,Wim Timens,Nikolaos Tzanakis,Vachier,A. M. Vignola,Louise Watson,G Yourgioti,Enfumosa Study Grp +45 more
TL;DR: It is suggested that severe asthma might be a different form of asthma rather than an increase in asthma symptoms, and longitudinal studies and interventions are needed to define the mechanisms in severe asthma.
Journal ArticleDOI
Tiotropium in Asthma Poorly Controlled with Standard Combination Therapy
Huib A. M. Kerstjens,Michael Engel,Ronald Dahl,Pierluigi Paggiaro,E Beck,Mark Vandewalker,Ralf Sigmund,Wolfgang Seibold,Petra Moroni-Zentgraf,Eric D. Bateman +9 more
TL;DR: In patients with poorly controlled asthma despite the use of inhaled glucocorticoids and LABAs, the addition of tiotropium significantly increased the time to the first severe exacerbation and provided modest sustained bronchodilation.
Journal ArticleDOI
Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma - A pilot study 164/rccm.200206-5250C
Johan Kips,Brian J. O'Connor,Stephen J. Langley,Ashley Woodcock,Huib A. M. Kerstjens,Dirkje S. Postma,Mel Danzig,Francis Cuss,Romain Pauwels +8 more
TL;DR: It is concluded that SCH55700 is a biologically active anti-human IL-5 antibody that can be safely used in severe steroid-treated asthma and its therapeutic potential needs to be addressed in specifically designed efficacy trials.
Journal ArticleDOI
Efficacy and safety of a recombinant anti‐immunoglobulin E antibody (omalizumab) in severe allergic asthma
Stephen T. Holgate,A.G. Chuchalin,J. Hebert,Jan Lötvall,G.B. Persson,Kian Fan Chung,Jean Bousquet,Huib A. M. Kerstjens,Howard Fox,J. Thirlwell,G. Della Cioppa +10 more
TL;DR: Patients with severe asthma are often inadequately controlled on existing anti‐asthma therapy, constituting an unmet clinical need, and this work aims to address that need.