K
Karine Andreau
Researcher at Paris Diderot University
Publications - 22
Citations - 1864
Karine Andreau is an academic researcher from Paris Diderot University. The author has contributed to research in topics: Programmed cell death & Apoptosis. The author has an hindex of 16, co-authored 21 publications receiving 1734 citations. Previous affiliations of Karine Andreau include Sorbonne & University of Paris.
Papers
More filters
Journal ArticleDOI
Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion
Patricia Boya,Karine Andreau,Delphine Poncet,Naoufal Zamzami,Jean-Luc Perfettini,Didier Métivier,David M. Ojcius,Marja Jäättelä,Guido Kroemer +8 more
TL;DR: The data indicate that mitochondria are indispensable for cell death initiated by lysosomal destabilization, as detected by the release of cytochrome c.
Journal ArticleDOI
Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine
Patricia Boya,Rosa-Ana Gonzalez-Polo,Delphine Poncet,Karine Andreau,Helena L. A. Vieira,Thomas Roumier,Jean-Luc Perfettini,Guido Kroemer +7 more
TL;DR: It is shown that hydroxychloroquine induces signs of lysosomal membrane permeabilization (LMP), and that Bax/Bak-dependent MMP is a critical step of LMP-induced cell death.
Journal ArticleDOI
Carbon black and titanium dioxide nanoparticles elicit distinct apoptotic pathways in bronchial epithelial cells
Salik Hussain,Salik Hussain,Leen C.J. Thomassen,Ioana Ferecatu,Marie-Caroline Borot,Karine Andreau,Johan A. Martens,Jocelyne Fleury,Armelle Baeza-Squiban,Francelyne Marano,Sonja Boland +10 more
TL;DR: Both CB and TiO2 NPs induce apoptotic cell death in bronchial epithelial cells although the final outcome is similar (apoptosis), the molecular pathways activated by NPs differ depending upon the chemical nature of the NPs.
Journal ArticleDOI
Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope
Maria Castedo,Thomas Roumier,Julià Blanco,Karine F. Ferri,Jordi Barretina,Lionel A. Tintignac,Karine Andreau,Jean-Luc Perfettini,Alessandra Amendola,Roberta Nardacci,Philip R. LeDuc,Donald E. Ingber,Sabine Druillennec,Bernard P. Roques,Serge A. Leibovitch,Montserrat Vilella-Bach,Jie Chen,José A. Esté,Nazanine Modjtahedi,Mauro Piacentini,Guido Kroemer +20 more
TL;DR: HIV‐1 elicits a pro‐apoptotic signal transduction pathway relying on the sequential action of cyclin B–Cdk1, mTOR and p53, which prevents karyogamy, m TOR activation, p53S15 phosphorylation and apoptosis.
Journal ArticleDOI
The chemopreventive agent N -(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family
Patricia Boya,Maria Celia Morales,Rosa-Ana Gonzalez-Polo,Karine Andreau,Isabelle Gourdier,Jean-Luc Perfettini,Nathanael Larochette,Aurélien Deniaud,Fanny Baran-Marszak,Remy Fagard,Jean Feuillard,Aintzane Asumendi,Martine Raphael,Bernard Pau,Catherine Brenner,Guido Kroemer +15 more
TL;DR: Data indicate that 4-HPR induces MMP through an ROS-mediated pathway that involves the obligatory contribution of the proapopotic Bcl-2 family members Bax and/or Bak.