K
Kathleen K. Sulik
Researcher at University of North Carolina at Chapel Hill
Publications - 114
Citations - 9312
Kathleen K. Sulik is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Fetal alcohol syndrome & Forebrain. The author has an hindex of 56, co-authored 114 publications receiving 8802 citations. Previous affiliations of Kathleen K. Sulik include National Institutes of Health & Dalhousie University.
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Journal ArticleDOI
Fetal Alcohol Syndrome: Embryogenesis in a Mouse Model
TL;DR: When two small doses of ethanol were administered to pregnant mice during the gastrulation stage of embryogenesis, the embryos developed craniofacial malformations closely resembling those seen in the human fetal alcohol syndrome.
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Teratogens and craniofacial malformations: relationships to cell death.
TL;DR: It is proposed that the pattern of craniofacial malformations is related to the particular vulnerability of cells in the vicinity of normal programmed cell death, which represents an important, yet little appreciated, mechanism of teratogenesis.
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Morphogenesis of the murine node and notochordal plate.
Kathleen K. Sulik,D. B. Dehart,Takayuki Inagaki,J. L. Carson,T. Vrablic,K. Gesteland,Gary C. Schoenwolf +6 more
TL;DR: The morphology of the murine notochordal plate and labeling studies support the concept of origin and rostrocaudal elongation of this structure in large part by accretion of cells from the node, and provide strong evidence that the ventral layer of the node forms notochords whereas the dorsal layer forms floor plate of the neural tube.
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Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function.
Mohamed Jaber,Walter J. Koch,Howard A. Rockman,Bradley R. Smith,Richard A. Bond,Kathleen K. Sulik,John Ross,Robert J. Lefkowitz,Marc G. Caron,Bruno Giros,Bruno Giros +10 more
TL;DR: It is demonstrated that beta ARK1 appears to be the predominant GRK in early embryogenesis and that it plays a fundamental role in cardiac development.
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Genesis of alcohol-induced craniofacial dysmorphism.
TL;DR: The development of an FAS mouse model whose craniofacial features are remarkably similar to those of affected humans is reviewed, based on short-term maternal treatment with a high dosage of ethanol at stages of pregnancy that are equivalent to Weeks 3 and 4 of human gestation.