T
Thomas E. Van Dyke
Researcher at The Forsyth Institute
Publications - 289
Citations - 24056
Thomas E. Van Dyke is an academic researcher from The Forsyth Institute. The author has contributed to research in topics: Periodontitis & Inflammation. The author has an hindex of 71, co-authored 265 publications receiving 20666 citations. Previous affiliations of Thomas E. Van Dyke include Boston University & Beth Israel Deaconess Medical Center.
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Resolving inflammation : dual anti-inflammatory and pro-resolution lipid mediators
TL;DR: New cellular and molecular mechanisms for the resolution of inflammation are presented, revealing key roles for eicosanoids, such as lipoxins, and recently discovered families of endogenous chemical mediators, termed resolvins and protectins, which have anti-inflammatory and pro-resolution properties.
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Inflammatory and immune pathways in the pathogenesis of periodontal disease.
TL;DR: Current knowledge of the host response in periodontitis is delineated to delineate the role of innate immunity, the failure of acute inflammation to resolve (thus becoming chronic), the cytokine pathways that regulate the activation of acquired immunity and the cells and products of the immune system are considered.
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Cutting Edge: Different Toll-Like Receptor Agonists Instruct Dendritic Cells to Induce Distinct Th Responses via Differential Modulation of Extracellular Signal-Regulated Kinase-Mitogen-Activated Protein Kinase and c-Fos
Sudhanshu Agrawal,Anshu Agrawal,Barbara L. Doughty,Andrew Gerwitz,John Blenis,Thomas E. Van Dyke,Bali Pulendran +6 more
TL;DR: It is demonstrated that distinct Toll-like receptor (TLR) ligands instruct human DCs to induce distinct Th cell responses by differentially modulating mitogen-activated protein kinase signaling.
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Periodontitis and atherosclerotic cardiovascular disease: consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases.
TL;DR: There is consistent and strong epidemiologic evidence that periodontitis imparts increased risk for future cardiovascular disease; and while in vitro, animal and clinical studies do support the interaction and biological mechanism, intervention trials to date are not adequate to draw further conclusions.
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Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions
Iain L. C. Chapple,Brian L. Mealey,Thomas E. Van Dyke,P. Mark Bartold,Henrik Dommisch,Peter Eickholz,Maria L. Geisinger,Robert J. Genco,Michael Glogauer,Moshe Goldstein,Terrence J. Griffin,Palle Holmstrup,Georgia K. Johnson,Yvonne L. Kapila,Niklaus P. Lang,Joerg Meyle,Shinya Murakami,Jacqueline M. Plemons,Giuseppe Alexandre Romito,Lior Shapira,Dimitris N. Tatakis,Wim Teughels,Leonardo Trombelli,Clemens Walter,Gernot Wimmer,Pinelopi Xenoudi,Hiromasa Yoshie +26 more
TL;DR: While gingival health and gingivitis have many clinical features, case definitions are primarily predicated on presence or absence of bleeding on probing, which creates differences in the way in which a "case" of gedival health or gingIVitis is defined for clinical practice as opposed to epidemiologically in population prevalence surveys.