K
Kati Ylitalo
Researcher at Helsinki University Central Hospital
Publications - 22
Citations - 1146
Kati Ylitalo is an academic researcher from Helsinki University Central Hospital. The author has contributed to research in topics: Intima-media thickness & Hyperlipidemia. The author has an hindex of 16, co-authored 22 publications receiving 1134 citations. Previous affiliations of Kati Ylitalo include University of Helsinki.
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Journal ArticleDOI
Linkage of familial combined hyperlipidaemia to chromosome 1q21-q23
Päivi Pajukanta,Ilpo Nuotio,Joseph D. Terwilliger,Kimmo Porkka,Kati Ylitalo,Jussi Pihlajamäki,Aki J. Suomalainen,Ann-Christine Syvänen,Terho Lehtimäki,Jorma Viikari,Markku Laakso,Marja-Riitta Taskinen,Christian Ehnholm,Leena Peltonen +13 more
TL;DR: The identification of a mouse combined hyperlipidaemia locus in the syntenic region of the mouse genome is reported, thus further implicating a gene in this region in the aetiology of FCHL.
Journal ArticleDOI
Genomewide Scan for Familial Combined Hyperlipidemia Genes in Finnish Families, Suggesting Multiple Susceptibility Loci Influencing Triglyceride, Cholesterol, and Apolipoprotein B Levels
Päivi Pajukanta,Joseph D. Terwilliger,Markus Perola,Tero Hiekkalinna,Ilpo Nuotio,Pekka Ellonen,Maija Parkkonen,Jaana Hartiala,Kati Ylitalo,Jussi Pihlajamäki,Kimmo Porkka,Markku Laakso,Jorma Viikari,Christian Ehnholm,Marja-Riitta Taskinen,Leena Peltonen +15 more
TL;DR: Additional putative loci influencing FCHL in Finnish families, some potentially affecting TG levels and some potentially affected TC or apoB levels are suggested.
Journal ArticleDOI
Genome scans provide evidence for low-HDL-C loci on chromosomes 8q23, 16q24.1-24.2, and 20q13.11 in Finnish families.
Aino Soro,Päivi Pajukanta,Heidi E. Lilja,Kati Ylitalo,Tero Hiekkalinna,Markus Perola,Rita M. Cantor,Jorma Viikari,Marja-Riitta Taskinen,Leena Peltonen,Leena Peltonen +10 more
TL;DR: Evidence for linkage between the low-HDL-C trait and three loci is found, in a pooled data analysis of families with low HDL-C and FCHL, in an independent sample group of 29 Finnish families that were ascertained for familial combined hyperlipidemia.
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Circulating Oxidized Low-Density Lipoprotein and Its Association With Carotid Intima-Media Thickness in Asymptomatic Members of Familial Combined Hyperlipidemia Families
TL;DR: Serum LDL cholesterol, apoB levels, and 8-isoprostane were the most important determinants of Ox-LDL, which is independently associated with carotid IMT in asymptomatic F CHL family members and can be used as a marker of early atherosclerosis in FCHL.
Journal ArticleDOI
LDL particle size in familial combined hyperlipidemia: effects of serum lipids, lipoprotein-modifying enzymes, and lipid transfer proteins.
Juha Vakkilainen,Matti Jauhiainen,Kati Ylitalo,Ilpo Nuotio,Jorma Viikari,Christian Ehnholm,Marja-Riitta Taskinen +6 more
TL;DR: It is concluded that serum triglyceride concentration is strongly correlated with LDL size in affected FCHL subjects, and after adjustment for serum triglycerides, HL and CETP activities are associated with HDL size in F CHL.