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Ann-Christine Syvänen

Researcher at Science for Life Laboratory

Publications -  349
Citations -  43207

Ann-Christine Syvänen is an academic researcher from Science for Life Laboratory. The author has contributed to research in topics: Single-nucleotide polymorphism & Genome-wide association study. The author has an hindex of 88, co-authored 348 publications receiving 40056 citations. Previous affiliations of Ann-Christine Syvänen include Veterans Health Administration & King's College London.

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Genetic studies of body mass index yield new insights for obesity biology

Adam E. Locke, +481 more
TL;DR: This paper conducted a genome-wide association study and meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals.
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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Andrew P. Morris, +232 more
- 01 Sep 2012 - 
TL;DR: This article conducted a meta-analysis of genetic variants on the Metabochip, including 34,840 cases and 114,981 controls, overwhelmingly of European descent, and identified ten previously unreported T2D susceptibility loci, including two showing sex-differentiated association.
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Transcriptome and genome sequencing uncovers functional variation in humans

Tuuli Lappalainen, +64 more
- 26 Sep 2013 - 
TL;DR: Se sequencing and deep analysis of messenger RNA and microRNA from lymphoblastoid cell lines of 462 individuals from the 1000 Genomes Project—the first uniformly processed high-throughput RNA-sequencing data from multiple human populations with high-quality genome sequences discover extremely widespread genetic variation affecting the regulation of most genes.
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Defining the role of common variation in the genomic and biological architecture of adult human height

Andrew R. Wood, +444 more
- 01 Nov 2014 - 
TL;DR: This article identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height, and all common variants together captured 60% of heritability.
Journal Article

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (vol 42, pg 105, 2010)

Josée Dupuis, +303 more
- 01 May 2010 -