K
Katrin Hahn
Researcher at Charité
Publications - 43
Citations - 1055
Katrin Hahn is an academic researcher from Charité. The author has contributed to research in topics: Medicine & Polyneuropathy. The author has an hindex of 10, co-authored 37 publications receiving 872 citations.
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Journal ArticleDOI
Heterozygous Arg753Gln Polymorphism of Human TLR-2 Impairs Immune Activation by Borrelia burgdorferi and Protects from Late Stage Lyme Disease
Nicolas W.J. Schröder,Isabel Diterich,Antje Zinke,Jana Eckert,Christian Draing,Volker von Baehr,Dieter Hassler,Susanne Priem,Katrin Hahn,Kathrin S. Michelsen,Thomas Hartung,Gerd R Burmester,Ulf B. Göbel,Corinna Hermann,Ralf R. Schumann +14 more
TL;DR: It is shown that TNF-α induction by Borrelia lysate was impaired in heterozygous TLR-2 knockout mice, while reactivity to lipoteichoic acid, another TLR -2 ligand signaling via TLr-2/TLR-6 heterodimers, was unaffected, suggesting that Arg753Gln may protect from the development of late stage LD due to a reduced signaling viaTLR/TLr-1.
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HIV-1-associated neurocognitive disorder: epidemiology, pathogenesis, diagnosis, and treatment
Christian Eggers,Gabriele Arendt,Katrin Hahn,Ingo W. Husstedt,Matthias Maschke,Eva Neuen-Jacob,Mark Obermann,Thorsten Rosenkranz,Eva Schielke,Elmar Straube +9 more
TL;DR: An overview of the current concepts in the field of HAND is given and suggestions for the diagnostic and therapeutic management are provided.
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A placebo-controlled trial of gabapentin for painful HIV-associated sensory neuropathies
Katrin Hahn,G Arendt,Johann S. Braun,H-J von Giesen,Ingo W. Husstedt,Matthias Maschke,M E Straube,Eva Schielke +7 more
TL;DR: GBP was more effective than placebo in reducing pain and sleep interference in patients with HIV-SN, and was generally well tolerated.
Journal ArticleDOI
Phosphorylated α-synuclein in skin nerve fibres differentiates Parkinson’s disease from multiple system atrophy
TL;DR: In this in vivo study, skin from the ventral forearm of 10 patients with multiple system atrophy and 10 with Parkinson's disease, together with six control subjects with essential tremor, were examined and phosphorylated SNCA deposits in skin sympathetic nerve fibres and dermal nerve fibre density were assessed.
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Optic radiation damage in multiple sclerosis is associated with visual dysfunction and retinal thinning – an ultrahigh-field MR pilot study
Tim Sinnecker,Timm Oberwahrenbrock,Imke Metz,Hanna Zimmermann,Caspar F. Pfueller,Lutz Harms,Klemens Ruprecht,Caren Ramien,Katrin Hahn,Wolfgang Brück,Thoralf Niendorf,Friedemann Paul,Alexander U. Brandt,Jan Dörr,Jens Wuerfel +14 more
TL;DR: Anterior visual pathway damage, but also (subclinical) optic radiation integrity loss detectable by 7 T MRI are common findings in MS that are mutually affected.