K
Kazuo Ohuchi
Researcher at Tohoku University
Publications - 139
Citations - 3615
Kazuo Ohuchi is an academic researcher from Tohoku University. The author has contributed to research in topics: Prostaglandin E2 & Histamine. The author has an hindex of 32, co-authored 139 publications receiving 3486 citations. Previous affiliations of Kazuo Ohuchi include Yasuda Women's University.
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Journal ArticleDOI
Mice lacking histidine decarboxylase exhibit abnormal mast cells
Hiroshi Ohtsu,Satoshi Tanaka,Tadashi Terui,Yoshio Hori,Yoko Makabe-Kobayashi,Gunnar Pejler,Elena Tchougounova,Lars Hellman,Marina Gertsenstein,Noriyasu Hirasawa,Eiko Sakurai,Edit I. Buzás,Péter Kovács,György Csaba,Ágnes Kittel,Mikiko Okada,Masahiro Hara,Lynn Mar,Keiko Numayama-Tsuruta,Satsuki Ishigaki-Suzuki,Kazuo Ohuchi,Atsushi Ichikawa,András Falus,Takehiko Watanabe,Andras Nagy,Andras Nagy +25 more
TL;DR: These HDC‐deficient mice are viable and fertile but exhibit a decrease in the numbers of mast cells while the remaining mast cells show an altered morphology and reduced granular content.
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Novel Roles of CpG Oligodeoxynucleotides as a Leader for the Sampling and Presentation of CpG-Tagged Antigen by Dendritic Cells
Hidekazu Shirota,Kunio Sano,Noriyasu Hirasawa,Tadashi Terui,Kazuo Ohuchi,Toshio Hattori,Kunio Shirato,Gen Tamura +7 more
TL;DR: Results indicate that CpG conjugated to Ag exhibit novel joint properties as promoters of Ag uptake and DC activators, thereby potentiating the ability of DCs to generate Th1 cells.
Journal ArticleDOI
Antiinflammatory actions of ephedrines in acute inflammations.
TL;DR: Hind-paw edema induced by histamine, serotonin, bradykinin and prostaglandin E was suppressed by these alkaloids, showing that they exert the antiinflammatory activity at the early exudative stage of inflammation.
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Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum.
Yong Pil Kim,Eun Bang Lee,Seung Yeun Kim,Da Wei Li,Hyun Seung Ban,Soon Sung Lim,Kuk Hyun Shin,Kazuo Ohuchi +7 more
TL;DR: Platycodin D, isolated from the root of Platycodon grandiflorum A. DC.
Journal ArticleDOI
Inhibitory Effects of Isorhamnetin-3-O-β- D -glucoside from Salicornia herbacea on Rat Lens Aldose Reductase and Sorbitol Accumulation in Streptozotocin-Induced Diabetic Rat Tissues
TL;DR: Results indicate that compound 1 from S. herbacea is a leading compound for further study as a new drug for the prevention and/or treatment of diabetes and its complications.