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Ágnes Kittel
Researcher at Hungarian Academy of Sciences
Publications - 111
Citations - 10702
Ágnes Kittel is an academic researcher from Hungarian Academy of Sciences. The author has contributed to research in topics: Microvesicles & Blood–brain barrier. The author has an hindex of 37, co-authored 105 publications receiving 8929 citations. Previous affiliations of Ágnes Kittel include Boston University.
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Journal ArticleDOI
Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles
Bence György,Tamás G. Szabó,Maria Pasztoi,Maria Pasztoi,Zsuzsanna Pál,Petra Misják,Borbala Aradi,Valéria László,Éva Pállinger,Éva Pállinger,Erna Pap,Ágnes Kittel,György Nagy,András Falus,András Falus,Edit I. Buzás +15 more
TL;DR: A comprehensive overview of extracellular vesicles is given in this article, where the authors compare results from meta-analyses of published proteomic studies on membrane Vesicles.
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The precursor protein of non-Aβ component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system
Akihiko Iwai,Eliezer Masliah,Makoto Yoshimoto,Nianfeng Ge,Lisa A. Flanagan,H.A.Rohan de Silva,Ágnes Kittel,Tsunao Saitoh +7 more
TL;DR: NACP sequence showed 95% identity with that of rat synuclein 1, a synaptic/nuclear protein previously identified in rat brain, and good homology with Torpedo syn DNA from the electric organ synapse and bovine phosphoneuroprotein 14 (PNP-14), a brain-specific protein present in synapses, suggesting that synaptic aberration observed in senile plaques might be involved in amyloidogenesis in Alzheimer's disease.
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Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomes
Rossella Crescitelli,Cecilia Lässer,Tamás G. Szabó,Ágnes Kittel,Maria Eldh,Irma Dianzani,Edit I. Buzás,Jan Lötvall +7 more
TL;DR: The authors' results demonstrate that centrifugation-based protocols are simple and fast systems to distinguish subpopulations of extracellular vesicles, but they are indistinguishable using CD63-coated beads for flow cytometry analysis.
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A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes
Shinsuke Nakagawa,Mária A. Deli,Hiroko Kawaguchi,Takeshi Shimizudani,Takanori Shimono,Ágnes Kittel,Kunihiko Tanaka,Masami Niwa +7 more
TL;DR: The new syngeneic BBB model, which is the first model to incorporate pericytes in a triple co-culture setting, can be a useful tool for research on BBB physiology and pathology and to test candidate compounds for centrally acting drugs.
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Isolation of Exosomes from Blood Plasma: Qualitative and Quantitative Comparison of Ultracentrifugation and Size Exclusion Chromatography Methods.
Tamás Baranyai,Kata Herczeg,Zsófia Onódi,István Voszka,Károly Módos,Nikolett Marton,György Nagy,Imre Mäger,Imre Mäger,Matthew J.A. Wood,Samir El Andaloussi,Samir El Andaloussi,Zoltán Pálinkás,Vikas Kumar,Péter Nagy,Ágnes Kittel,Edit I. Buzás,Péter Ferdinandy,Zoltán Giricz +18 more
TL;DR: It is shown that it is feasible to isolate exosomes from blood plasma by SEC without significant albumin contamination albeit with low vesicle yield.