K
Ke Xu
Researcher at Yale University
Publications - 129
Citations - 9268
Ke Xu is an academic researcher from Yale University. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 37, co-authored 103 publications receiving 8354 citations. Previous affiliations of Ke Xu include Veterans Health Administration & National Institutes of Health.
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Journal ArticleDOI
Identification of HIV infection-related DNA methylation sites and advanced epigenetic aging in HIV-positive, treatment-naive U.S. veterans.
Kristin N. Nelson,Qin Hui,David Rimland,Ke Xu,Matthew S. Freiberg,Amy C. Justice,Vincent C. Marconi,Yan V. Sun +7 more
TL;DR: ART treatment-naive HIV-positive individuals have significantly older DNAm age compared to HIV-negative individuals in the Veterans Aging Cohort Study cohort, indicating that longitudinal changes in DNA methylation age are highly variable across individuals after initiation of antiretroviral therapy.
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Preliminary analysis of positive and negative syndrome scale in ketamine-associated psychosis in comparison with schizophrenia
Ke Xu,Ke Xu,John H. Krystal,John H. Krystal,Yuping Ning,Da Chun Chen,Hongbo He,Daping Wang,Xiaoyin Ke,Xifan Zhang,Yi Ding,Yuping Liu,Ralitza Gueorguieva,Zuoheng Wang,Diana Limoncelli,Robert H. Pietrzak,Robert H. Pietrzak,Ismene L. Petrakis,Ismene L. Petrakis,Xiang Yang Zhang,Ni Fan +20 more
TL;DR: Evidence of similarity in symptom dimensions between ketamine psychosis and schizophrenia psychosis is provided, and the interpretations should be cautious because of potential confounding factors.
Journal ArticleDOI
Nucleotide sequence variation within the human tyrosine kinase B neurotrophin receptor gene: association with antisocial alcohol dependence.
Ke Xu,T. R. Anderson,K. M. Neyer,N Lamparella,G Jenkins,Zhifeng Zhou,Qiaoping Yuan,Matti Virkkunen,Robert H. Lipsky +8 more
TL;DR: A role for the NTRK2 gene in addiction in a Caucasian population with AD and a subtype of ASPD is supported in a Finnish Caucasian sample of 229 alcohol-dependent subjects with antisocial personality disorder and 287 healthy controls.
Journal ArticleDOI
Repeated ketamine administration alters N-methyl-d-aspartic acid receptor subunit gene expression: Implication of genetic vulnerability for ketamine abuse and ketamine psychosis in humans:
TL;DR: This work proposes that full sequencing of NMDA receptor genes may help explain individual vulnerability to ketamine abuse and ketamine-associated psychosis and proposes a potential mechanism where up-regulation ofNMDA receptors could produce cognitive deficits in chronic ketamines abuse patients.
Journal ArticleDOI
The profile of cognitive impairments in chronic ketamine users.
Xiaoyin Ke,Yi Ding,Ke Xu,Hongbo He,Daping Wang,Xuefeng Deng,Xifan Zhang,Yanling Zhou,Chao Zhou,Yuping Liu,Yuping Ning,Ni Fan +11 more
TL;DR: Chronic ketamine users had cognitive impairments across multiple domains, and word-reading score was positively correlated with education level, and negatively correlated with duration of ketamine use.