K
Ke Xu
Researcher at Yale University
Publications - 129
Citations - 9268
Ke Xu is an academic researcher from Yale University. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 37, co-authored 103 publications receiving 8354 citations. Previous affiliations of Ke Xu include Veterans Health Administration & National Institutes of Health.
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Journal ArticleDOI
Interaction between a functional MAOA locus and childhood sexual abuse predicts alcoholism and antisocial personality disorder in adult women.
TL;DR: MAOA seems to moderate the impact of childhood trauma on adult psychopathology in female subjects in the same way as previously shown among male subjects.
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Association between ADORA2A and DRD2 polymorphisms and caffeine-induced anxiety.
Emma Childs,Christa Hohoff,Jürgen Deckert,Jürgen Deckert,Ke Xu,Judith A. Badner,Harriet de Wit +6 more
TL;DR: Ass associations between self-reported anxiogenic effects of caffeine and variation in the genes for A2A (ADORA2A) and DRD2 (DRD2) receptors are examined to provide support for an association between an ADORA 2A polymorphism and self- reported anxiety after a moderate dose of caffeine.
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Association of the G1947A COMT (Val108/158Met) gene polymorphism with prefrontal P300 during information processing
Jürgen Gallinat,Malek Bajbouj,Thomas Sander,Peter Schlattmann,Ke Xu,Erica Ferro,David Goldman,Georg Winterer,Georg Winterer +8 more
TL;DR: The association of the frontal P300 amplitude with the G1947A COMT genotype further emphasizes the functional role of this SNP and suggests that the amount of noise in prefrontal neural networks during information processing might be in part under genetic control, which is mediated by dopamine.
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Nuclear factor κB is a critical determinant in N-methyl-D-aspartate receptor-mediated neuroprotection
Robert H. Lipsky,Ke Xu,Daming Zhu,Charles Kelly,Artin Terhakopian,Antonello Novelli,Ann M. Marini +6 more
TL;DR: Nuclear extracts prepared from neurons treated with NMDA and the double‐stranded NF‐κB oligonucleotide showed reduced DNA binding activity to the target sequence, supporting the idea that NF‐kkB may be involved in the transcriptional activation of the BDNF gene.
Journal ArticleDOI
DRD2 promoter region variation as a predictor of sustained response to antipsychotic medication in first-episode schizophrenia patients
Todd Lencz,Delbert Robinson,Ke Xu,Jenny M. Ekholm,Serge Sevy,Handan Gunduz-Bruce,Margaret G. Woerner,John M. Kane,David Goldman,Anil K. Malhotra +9 more
TL;DR: Findings suggest that variation in the D(2) receptor gene can, in part, explain variations in the timing of clinical response to antipsychotics in patients with first-episode schizophrenia.