K
Ke Xu
Researcher at Yale University
Publications - 129
Citations - 9268
Ke Xu is an academic researcher from Yale University. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 37, co-authored 103 publications receiving 8354 citations. Previous affiliations of Ke Xu include Veterans Health Administration & National Institutes of Health.
Papers
More filters
Journal ArticleDOI
Gender-specific effects of the catechol-O-methyltransferase Val108/158Met polymorphism on cognitive function in children.
TL;DR: This common polymorphism in the catechol-O-methyltransferase (COMT) gene may be one of the genes of small effect that contribute to normal variation in IQ and may contribute to risk for schizophrenia.
Journal ArticleDOI
DNA Melting Analysis for Detection of Single Nucleotide Polymorphisms
Robert H. Lipsky,C.M. Mazzanti,Joseph G. Rudolph,Ke Xu,Gopal Vyas,David Bozak,Marta Radel,David Goldman +7 more
TL;DR: DNA melting analysis (DM) was used successfully for variant detection, and two previously unknown SNPs were discovered by this approach, making it highly suitable for the large-scale detection of sequence variants.
Journal ArticleDOI
Using ancestry-informative markers to define populations and detect population stratification
TL;DR: The debate about the quantity and methods for selection of highly informative marker loci required to characterize populations that vary in substructure or the degree of admixture is focused on, and how these theoretically desirable approaches can be effectively put into practice is discussed.
Journal ArticleDOI
Association of Specific Haplotypes of D2 Dopamine Receptor Gene with Vulnerability to Heroin Dependence in 2 Distinct Populations
Ke Xu,Dirk Lichtermann,Robert H. Lipsky,Petra Franke,Xie-he Liu,Ying Hu,Liping Cao,Sibylle G. Schwab,Dieter B. Wildenauer,Claiton H D Bau,Erica Ferro,Will Astor,Thembi Finch,Jeanietta Terry,Julie Taubman,Wolfgang Maier,David Goldman +16 more
TL;DR: These results strongly support a role of DRD2 as a susceptibility gene with heroin dependence in Chinese patients and was associated with low risk ofHeroin dependence in Germans.
Journal ArticleDOI
Association of OPRM1 Functional Coding Variant With Opioid Use Disorder: A Genome-Wide Association Study.
Hang Zhou,Hang Zhou,Christopher T Rentsch,Christopher T Rentsch,Christopher T Rentsch,Zhongshan Cheng,Zhongshan Cheng,Rachel L. Kember,Rachel L. Kember,Yaira Z. Nunez,Yaira Z. Nunez,Richard Sherva,Janet P. Tate,Janet P. Tate,Cecilia Dao,Cecilia Dao,Ke Xu,Ke Xu,Renato Polimanti,Renato Polimanti,Lindsay A. Farrer,Amy C. Justice,Amy C. Justice,Henry R. Kranzler,Henry R. Kranzler,Joel Gelernter +25 more
TL;DR: A genome-wide meta-analysis identified a significant association of OUD with an OPRM1 variant, which was replicated in 2 independent samples and revealed associated pleiotropic characteristics.