K
Ke Xu
Researcher at Yale University
Publications - 129
Citations - 9268
Ke Xu is an academic researcher from Yale University. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 37, co-authored 103 publications receiving 8354 citations. Previous affiliations of Ke Xu include Veterans Health Administration & National Institutes of Health.
Papers
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Journal ArticleDOI
The Effects of BDNF Val66Met Gene Polymorphism on Serum BDNF and Cognitive Function in Methamphetamine-Dependent Patients and Normal Controls: A Case-Control Study.
Hang Su,Jingyan Tao,Jie Zhang,Ying Xie,Wang Yue,Yu Zhang,Bin Han,Yuling Lu,Haiwei Sun,Youdan Wei,Shengzhen Zou,Wenxiu Wu,Jiajia Zhang,Ke Xu,Xiang Yang Zhang,Xiang Yang Zhang,Jincai He +16 more
TL;DR: Significant impairment on some aspects of cognitive function and increased BDNF levels in methamphetamine-dependent patients as well as genotypic differences in the relationships betweenBDNF levels and RBANS scores on the BDNF Val66Met polymorphism only in these patients are demonstrated.
Journal ArticleDOI
Gene selection for optimal prediction of cell position in tissues from single-cell transcriptomics data
Jovan Tanevski,Jovan Tanevski,Thin Nguyen,Buu Truong,Nikos Karaiskos,Mehmet Eren Ahsen,Mehmet Eren Ahsen,Xinyu Zhang,Chang Shu,Ke Xu,Xiaoyu Liang,Ying Hu,Hoang Vv Pham,Li Xiaomei,Thuc Duy Le,Adi L. Tarca,Gaurav Bhatti,Roberto Romero,Nestoras Karathanasis,Phillipe Loher,Yang Chen,Zhengqing Ouyang,Disheng Mao,Yuping Zhang,Maryam Zand,Jianhua Ruan,Christoph Hafemeister,Peng Qiu,Peng Qiu,Duc A. Tran,Tin Nguyen,Attila Gábor,Thomas Yu,Justin Guinney,Enrico Glaab,Roland Krause,Peter Banda,Gustavo Stolovitzky,Nikolaus Rajewsky,Julio Saez-Rodriguez,Julio Saez-Rodriguez,Pablo Meyer +41 more
TL;DR: The DREAM Single-Cell Transcriptomics challenge focused on the spatial reconstruction of cells from the Drosophila embryo from scRNAseq data, leveraging as silver standard, genes with in situ hybridization data from the Berkeley Droseophila Transcription Network Project reference atlas.
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Validating Harmful Alcohol Use as a Phenotype for Genetic Discovery Using Phosphatidylethanol and a Polymorphism in ADH1B.
Amy C. Justice,Amy C. Justice,Kathleen A. McGinnis,Janet P. Tate,Ke Xu,Ke Xu,William C. Becker,William C. Becker,Hongyu Zhao,Joel Gelernter,Joel Gelernter,Henry R. Kranzler +11 more
TL;DR: EHR data can be used to identify complex phenotypes such as harmful alcohol use and the validity of the phenotype may be enhanced through the use of longitudinal trajectories.
Journal ArticleDOI
Decreased Blood Levels of Oxytocin in Ketamine-Dependent Patients During Early Abstinence.
Ming-Chyi Huang,Ming-Chyi Huang,Lian-Yu Chen,Hu-Ming Chang,Xiao-Yu Liang,Chih-Ken Chen,Chih-Ken Chen,Wan-Ju Cheng,Ke Xu +8 more
TL;DR: It is suggested that oxytocin system dysregulated following chronic ketamine abuse and might provide insight in evaluating the potential therapeutic use of oxytocIn for treating ketamine dependence.
Journal ArticleDOI
Irritable assault and variation in the COMT gene.
TL;DR: Limited support is provided for a role of COMT in modulating aggressive behavior among people with axis II personality disorders and extended to people with personality disorders.