K
Ke Xu
Researcher at Yale University
Publications - 129
Citations - 9268
Ke Xu is an academic researcher from Yale University. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 37, co-authored 103 publications receiving 8354 citations. Previous affiliations of Ke Xu include Veterans Health Administration & National Institutes of Health.
Papers
More filters
Journal ArticleDOI
A new monocyte epigenetic clock reveals nonlinear effects of alcohol consumption on biological aging in three independent cohorts (N = 2242)
TL;DR: A novel monocyte-based DNA methylation clock (MonoDNAmAge) is developed to assess the impact of alcohol consumption on monocyte age and the results suggest a nonlinear relationship between alcohol consumption and epigenetic age alteration.
Journal ArticleDOI
Rater Evaluations for Psychiatric Instruments and Cultural Differences: The Positive and Negative Syndrome Scale in China and the United States
Neil Krishan Aggarwal,Xiang Yang Zhang,Elina Stefanovics,Elina Stefanovics,Da Chun Chen,Mei Hong Xiu,Ke Xu,Ke Xu,Robert A. Rosenheck,Robert A. Rosenheck +9 more
TL;DR: Differences seem to be best explained by both cultural differences in patient clinical presentations and varying American and Chinese cultural values affecting rater judgment.
Journal ArticleDOI
Epigenome-wide association study of posttraumatic stress disorder identifies novel loci in U.S. military veterans
Joel Gelernter,Zhongshan Cheng,Matthew J. Girgenti,Ke Xu,Xin Zhang,Shyamalika Gopalan,Hang Zhou,Steven M. Southwick,Matthew J. Ronald S. Matthew J. John H. Janitza L. Friedman Duman Girgenti Krystal Montalvo-Ortiz,Matthew J. Friedman,Ronald S. Duman,John H. Krystal,Janitza L. Montalvo-Ortiz,Robert H. Pietrzak +13 more
TL;DR: In this article , the authors performed a single-sample epigenome-wide association study (EWAS) of PTSD and identified six genome-wide significant (GWS) sites associated with past-month PTSD and three CpGs with lifetime PTSD.
Posted ContentDOI
DNA methylation mediates the effect of cocaine use on HIV severity
TL;DR: DNAm played a mediation role between cocaine use and HIV severity in a veteran population and these genes were enriched in pathways involving in viral process and response to cytokine.
Journal ArticleDOI
Genomics and variation of ionotropic glutamate receptors: implications for neuroplasticity.
TL;DR: Two approaches were used to identify sequence variants in ionotropic glutamate receptor (IGR) genes: high-throughput screening and resequencing techniques, and “information mining” of public and private sequence databases.