K
Ke Xu
Researcher at Yale University
Publications - 129
Citations - 9268
Ke Xu is an academic researcher from Yale University. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 37, co-authored 103 publications receiving 8354 citations. Previous affiliations of Ke Xu include Veterans Health Administration & National Institutes of Health.
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Journal ArticleDOI
Imaging genomics applied to anxiety, stress response, and resiliency
TL;DR: Individuals with Met158 genotypes are more sensitive to pain stress and have diminished ability to upregulate opioid release after pain/stress, suggesting that functional variants of 5-HTT and COMT impact brain functions involved in stress and anxiety.
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DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty
TL;DR: An epigenome-wide association analysis of IDU and HCV in HIV-infected individuals finds that their associated methylation signatures inform HIV frailty and discriminate HIV pathophysiologic frailty.
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Epigenome-wide association analysis revealed that SOCS3 methylation influences the effect of cumulative stress on obesity.
TL;DR: It is suggested that aberrant in DNA methylation is associated with body weight and that methylation of SOCS3 moderates the effect of cumulative stress on obesity.
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Machine learning selected smoking-associated DNA methylation signatures that predict HIV prognosis and mortality
Xinyu Zhang,Ying Hu,Bradley E. Aouizerat,Gang Peng,Vincent C. Marconi,Michael J. Corley,Todd Hulgan,Kendall J. Bryant,Hongyu Zhao,John H. Krystal,Amy C. Justice,Ke Xu +11 more
TL;DR: It is demonstrated that smoking-associated DNA methylation features in white blood cells predict HIV infection-related clinical outcomes in a population living with HIV.
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Similar psychotic and cognitive profile between ketamine dependence with persistent psychosis and schizophrenia.
Wan-Ju Cheng,Chun Hsin Chen,C K Chen,Ming Chyi Huang,Robert H. Pietrzak,John H. Krystal,Ke Xu +6 more
TL;DR: The data suggest that the symptom profile and cognitive impairments associated with persisting psychosis due to chronic heavy ketamine abuse resemble those of schizophrenia, while KNP patients showed significantly less severe symptom profiles and cognitive impairment than KPP and SZ.