K
Kees Schoonderwoerd
Researcher at Erasmus University Rotterdam
Publications - 47
Citations - 1521
Kees Schoonderwoerd is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Lipase & Lipolysis. The author has an hindex of 23, co-authored 47 publications receiving 1390 citations.
Papers
More filters
Journal ArticleDOI
Early Exercise Training Normalizes Myofilament Function and Attenuates Left Ventricular Pump Dysfunction in Mice With a Large Myocardial Infarction
Monique C. de Waard,Jolanda van der Velden,Virginie Bito,Semir Ozdemir,Liesbeth Biesmans,Nicky M. Boontje,Dick H. W. Dekkers,Kees Schoonderwoerd,Hans Schuurbiers,Rini de Crom,Ger J.M. Stienen,Karin R. Sipido,Jos M. J. Lamers,Dirk J. Duncker +13 more
TL;DR: Early exercise in mice after a large MI has no effect on LV remodeling, but attenuates global LV dysfunction, which can be explained by the exercise-induced improvement of myofilament function.
Journal ArticleDOI
Riboflavin-responsive oxidative phosphorylation complex I deficiency caused by defective ACAD9: new function for an old gene.
Mike Gerards,Bianca J.C. van den Bosch,Katharina Danhauser,Valérie Serre,Michel van Weeghel,Ronald J.A. Wanders,Gerry A. F. Nicolaes,Wim Sluiter,Kees Schoonderwoerd,Hans R. Scholte,Holger Prokisch,Agnès Rötig,Irenaeus F.M. de Coo,Hubert J.M. Smeets +13 more
TL;DR: The data support a new function for ACAD9 in complex I function, making this gene an important new candidate for patients with complex I deficiency, which could be improved by riboflavin treatment.
Journal ArticleDOI
Post-natal myogenic and adipogenic developmental: defects and metabolic impairment upon loss of A-type lamins.
Nard Kubben,Jan Willem Voncken,Gonda Konings,Michel van Weeghel,Maarten M.G. van den Hoogenhof,Marion J.J. Gijbels,Arie van Erk,Kees Schoonderwoerd,Bianca J.C. van den Bosch,Vivian E. H. Dahlmans,Chantal Calis,Sander M. Houten,Tom Misteli,Yigal M. Pinto +13 more
TL;DR: It is indicated that defective early post-natal development critically contributes to the disease phenotypes in adult laminopathies.
Journal ArticleDOI
Exome sequencing reveals a novel Moroccan founder mutation in SLC19A3 as a new cause of early-childhood fatal Leigh syndrome
Mike Gerards,Rick Kamps,Jo van Oevelen,Iris B W Boesten,Eveline Jongen,Bart de Koning,Hans R. Scholte,Isabel B. de Angst,Kees Schoonderwoerd,Abdelaziz Sefiani,Ilham Ratbi,Wouter Coppieters,Latifa Karim,René de Coo,Bianca J.C. van den Bosch,Hubert J.M. Smeets +15 more
TL;DR: The data shows that SLC19A3 is a new candidate for mutation screening in patients with Leigh syndrome, who might benefit from high doses of thiamine and/or biotin, and especially, Moroccan patients withLeigh syndrome should be tested for the c.20C>A founder mutation in SLC 19A3.
Journal ArticleDOI
Nonsense mutations in CABC1/ADCK3 cause progressive cerebellar ataxia and atrophy.
Mike Gerards,Bianca J.C. van den Bosch,Chantal Calis,Kees Schoonderwoerd,Klaartje van Engelen,Marina A. J. Tijssen,René de Coo,Anneke J. van der Kooi,Hubert J.M. Smeets +8 more
TL;DR: The results indicate that CABC1 is an important candidate for mutation analysis in progressive cerebellar ataxia and atrophy on MRI to identify those patients, who may benefit from CoQ10 treatment.