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Holger Prokisch

Researcher at Technische Universität München

Publications -  400
Citations -  35984

Holger Prokisch is an academic researcher from Technische Universität München. The author has contributed to research in topics: Mitochondrial disease & Gene. The author has an hindex of 80, co-authored 361 publications receiving 29653 citations. Previous affiliations of Holger Prokisch include Capital Medical University & Ludwig Maximilian University of Munich.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Systematic identification of trans eQTLs as putative drivers of known disease associations

Harm-Jan Westra, +60 more
- 01 Oct 2013 - 
TL;DR: Variants associated with cholesterol metabolism and type 1 diabetes showed similar phenomena, indicating that large-scale eQTL mapping provides insight into the downstream effects of many trait-associated variants.
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ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

Sebastian Doll, +21 more
- 01 Jan 2017 - 
TL;DR: Pharmacological targeting of ACSL4 with thiazolidinediones, a class of antidiabetic compound, ameliorated tissue demise in a mouse model of ferroptosis, suggesting that ACSL 4 inhibition is a viable therapeutic approach to preventing ferroPTosis-related diseases.
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Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

Simone Wahl, +123 more
- 05 Jan 2017 - 
TL;DR: In this article, the authors used epigenome-wide association to show that body mass index (BMI), a key measure of adiposity, is associated with widespread changes in DNA methylation.
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Novel biomarkers for pre-diabetes identified by metabolomics

Rui Wang-Sattler, +44 more
- 01 Jan 2012 - 
TL;DR: Seven T2D‐related genes are identified that are associated with these three IGT‐specific metabolites by multiple interactions with four enzymes, and the expression levels of these enzymes correlate with changes in the metabolite concentrations linked to diabetes.