K
Kelsey M. Tyssowski
Researcher at Harvard University
Publications - 10
Citations - 467
Kelsey M. Tyssowski is an academic researcher from Harvard University. The author has contributed to research in topics: Premovement neuronal activity & Gene. The author has an hindex of 8, co-authored 10 publications receiving 308 citations. Previous affiliations of Kelsey M. Tyssowski include University of Tokyo.
Papers
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Journal ArticleDOI
Different Neuronal Activity Patterns Induce Different Gene Expression Programs
Kelsey M. Tyssowski,Nicholas R. DeStefino,Jin-Hyung Cho,Carissa J. Dunn,Robert G. Poston,Crista Carty,Richard D. Jones,Sarah M. Chang,Palmyra Romeo,Mary K. Wurzelmann,James M. Ward,Mark L. Andermann,Ramendra N. Saha,Ramendra N. Saha,Serena M. Dudek,Jesse M. Gray +15 more
TL;DR: The same mechanisms that establish the multi-wave temporal structure of gene induction also enable different gene sets to be induced by different activity durations and improve the understanding of activity-pattern-dependent synaptic plasticity.
Journal ArticleDOI
The polycomb component Ring1B regulates the timed termination of subcerebral projection neuron production during mouse neocortical development
Nao Morimoto-Suzki,Yusuke Hirabayashi,Kelsey M. Tyssowski,Jun Shinga,Miguel Vidal,Haruhiko Koseki,Yukiko Gotoh +6 more
TL;DR: It is shown that epigenetic regulation through Ring1B, an essential component of polycomb group (PcG) complex proteins, plays a key role in terminating NPC-mediated production of subcerebral projection neurons (SCPNs) and regulates the number of SCPNs.
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Blue Light Increases Neuronal Activity-Regulated Gene Expression in the Absence of Optogenetic Proteins.
TL;DR: Exposing mouse cortical cultures to as short as 1 h of blue light, but not red or green light, results in an increase in the expression of neuronal activity-regulated genes, suggesting that blue light stimulation is ill suited to long-term optogenetic experiments, especially those that measure transcription.
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Chromatin regulators of neural development
TL;DR: Recent papers that describe the roles of chromatin-level regulation, at both the local and global scale, in the development of the mouse brain are reviewed.
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The neuronal stimulation-transcription coupling map.
TL;DR: The current state of the stimulation-transcription coupling map as well as the transcriptional regulation that enables this coupling are described.