K
Ken Ichi Iyama
Researcher at Kumamoto University
Publications - 94
Citations - 3001
Ken Ichi Iyama is an academic researcher from Kumamoto University. The author has contributed to research in topics: Type IV collagen & Carcinoma. The author has an hindex of 30, co-authored 93 publications receiving 2799 citations. Previous affiliations of Ken Ichi Iyama include Okayama University.
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Journal ArticleDOI
Differential expression of two basement membrane collagen genes, COL4A6 and COL4A5, demonstrated by immunofluorescence staining using peptide-specific monoclonal antibodies.
Yoshifumi Ninomiya,Megumi Kagawa,Ken Ichi Iyama,Ichiro Naito,Yumiko Kishiro,Jerome M. Seyer,Manabu Sugimoto,Toshitaka Oohashi,Yoshikazu Sado +8 more
TL;DR: It is demonstrated that in human adult kidney the alpha 6(IV) chain was never detected in the glomerular basement membrane, whereas the basement membranes of the Bowman's capsules and distal tubules were positive.
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Identification of Chondromodulin I as a Novel Endothelial Cell Growth Inhibitor PURIFICATION AND ITS LOCALIZATION IN THE AVASCULAR ZONE OF EPIPHYSEAL CARTILAGE
Yuji Hiraki,Hiroyuki Inoue,Ken Ichi Iyama,Akihito Kamizono,Masanori Ochiai,Chisa Shukunami,Sadayo Iijima,Fujio Suzuki,Jun Kondo +8 more
TL;DR: P purification of an endothelial cell growth inhibitor from a guanidine extract of bovine epiphyseal cartilage suggests a regulatory role of ChM-I in vascular invasion during endochondral bone formation.
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The effect of a local application of fibroblast growth factor-2 on tendon-to-bone remodeling in rats with acute injury and repair of the supraspinatus tendon.
Junji Ide,Kenshi Kikukawa,Jun Hirose,Ken Ichi Iyama,Hidetoshi Sakamoto,Toru Fujimoto,Hiroshi Mizuta +6 more
TL;DR: The initial tendon-to-bone remodeling of repaired supraspinatus tendon in rats subjected to bilateral detachment was accelerated by a local application of FGF-2, indicating a clinically important improvement in rotator cuff repair.
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Double intratracheal instillation of keratinocyte growth factor prevents bleomycin-induced lung fibrosis in rats.
TL;DR: Double instillation of KGF prevented the loss of body weight and reduction in total lung capacity (TLC) due to Bleo, and markedly attenuated the protein accumulation and mRNA expression of collagen types I and III and the decreased expression of surfactant protein mRNAs in the fibrotic lesions of Bleo‐treated rats.
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The Effects of Fibroblast Growth Factor-2 on Rotator Cuff Reconstruction With Acellular Dermal Matrix Grafts
TL;DR: The remodeling of ADM grafts placed in rat rotator cuff tendon defects was accelerated by the local administration of FGF-2, which may result in improved histologic characteristics and biomechanical strength in ADm graft constructs in humans.