K
Kenji Matsumoto
Researcher at Saitama Medical University
Publications - 344
Citations - 12232
Kenji Matsumoto is an academic researcher from Saitama Medical University. The author has contributed to research in topics: Immunoglobulin E & Interleukin 33. The author has an hindex of 54, co-authored 319 publications receiving 10390 citations.
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Journal ArticleDOI
Role of Interleukin-33 in Innate-Type Immune Cells in Allergy
Susumu Nakae,Susumu Nakae,Hideaki Morita,Tatsukuni Ohno,Ken Arae,Kenji Matsumoto,Hirohisa Saito +6 more
TL;DR: Current knowledge regarding the pathogenic roles of IL-33 in the development of allergic inflammation is summarized by focusing on its effects on innate-type immune cells.
Journal ArticleDOI
Pathogenic role of CXCR7 in rheumatoid arthritis.
Kaori Watanabe,Mark E. T. Penfold,Akio Matsuda,Naho Ohyanagi,Kayoko Kaneko,Yoshishige Miyabe,Kenji Matsumoto,Thomas J. Schall,Nobuyuki Miyasaka,Toshihiro Nanki +9 more
TL;DR: CXCR7 and CXCR4 are both important for angiogenesis in RA synovium, making CX CR7 another potential target molecule for novel RAAngiogenesis-blocking therapies.
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Pepsin-Resistant 16-kD Buckwheat Protein Is Associated with Immediate Hypersensitivity Reaction in Patients with Buckwheat Allergy
Kazuko Tanaka,Kenji Matsumoto,Akira Akasawa,Toshiharu Nakajima,Takeshi Nagasu,Yoji Iikura,Hirohisa Saito +6 more
TL;DR: The 16-kD buckwheat protein was resistant to pepsin digestion and appeared to be responsible for IHR including anaphylaxis, while the pepsIn-sensitive 24-KD protein was responsible for CAP-FEIA but not IHR.
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Defensive effect of microRNA-200b/c against amyloid-beta peptide-induced toxicity in Alzheimer's disease models.
Sayuri Higaki,Masashi Muramatsu,Akio Matsuda,Kenji Matsumoto,Jun-ichi Satoh,Makoto Michikawa,Shumpei Niida +6 more
TL;DR: In this article, the function of miR-200 mRNAs was examined using microarray analysis of cortical tissue from Tg2576 transgenic mice, and it was shown that miR200mRNAs have lower toxic effects than other gene silencing methods, thus enhancing the expression of defensive miRNA could be an effective therapy.
Journal ArticleDOI
Selective down-regulation of high-affinity IgE receptor (FcεRI) α-chain messenger RNA among transcriptome in cord blood–derived versus adult peripheral blood–derived cultured human mast cells
Makoto Iida,Kenji Matsumoto,Hisashi Tomita,Toshiharu Nakajima,Akira Akasawa,Noriko Ohtani,Ning Lu Yoshida,Keiko Matsui,Akiko Nakada,Yuji Sugita,Yuji Shimizu,Shunichi Wakahara,Toru Nakao,Yasuyuki Fujii,Chisei Ra,Hirohisa Saito +15 more
TL;DR: The results suggest that IgE-mediated reactions may be restricted during early infancy through the selective inhibition of FcepsilonRIalpha transcription, which is probably committed at progenitor stages and is, at least in part, cytokine-insensitive.