K
Kevin E. Fogarty
Researcher at University of Massachusetts Medical School
Publications - 97
Citations - 7681
Kevin E. Fogarty is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Endosome & Ryanodine receptor. The author has an hindex of 47, co-authored 96 publications receiving 7276 citations.
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Calcium gradients in single smooth muscle cells revealed by the digital imaging microscope using Fura-2
TL;DR: The observed regulation of intranuclear Ca2+ in these contractile cells may be seen as a way to prevent fluctuation in Ca2-linked nuclear processes during the rise in cytoplasmic [Ca2+] which triggers contraction.
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The Intraflagellar Transport Protein IFT20 Is Associated with the Golgi Complex and Is Required for Cilia Assembly
TL;DR: It is shown here that the IFT20 subunit of the particle is localized to the Golgi complex in addition to the basal body and cilia where all previous IFT particle proteins had been found.
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Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria
Elena Rapizzi,Paolo Pinton,Gyorgy Szabadkai,Mariusz R. Wieckowski,Grégoire Vandecasteele,Geoff Baird,Richard A. Tuft,Kevin E. Fogarty,Rosario Rizzuto +8 more
TL;DR: Analysis of the role of the voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane in the transmission of Ca2+ signals between the ER and mitochondria reveals a novel function for the widely expressed VDAC channel, identifying it as a molecular component of the routes for Ca2+.
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MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis
TL;DR: This work describes a novel genetic mechanism in which a microRNA facilitates integration of a physiological stimulus with growth factor signalling in endothelial cells to guide angiogenesis.
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Calcium gradients underlying polarization and chemotaxis of eosinophils
TL;DR: Changes in intracellular free calcium ([Ca2+]i) in polarized eosinophils provide a basis for understanding the organization and local activity of cytoskeletal proteins thought to underlie the directed migration of many cells.