Kim Van Roey

TL;DR: All data manually curated by the MINT curators have been moved into the IntAct database at EMBL-EBI and are merged with the existing IntAct dataset.

TL;DR: Analysis of curated instances currently available in the Eukaryotic Linear Motif database suggest that functional SLiMs have higher levels of conservation than their surrounding residues, frequently evolve convergently, preferentially occur in disordered regions and often form a secondary structure when bound to their interaction partner.

TL;DR: The motif discovery portion of the ELM resource has added conservation, and structural attributes have been incorporated to aid users to discriminate biologically relevant motifs from stochastically occurring non-functional instances.

TL;DR: Interaction Modules Directing Cell Regulation Kim Van Roey, Bora Uyar,† Robert J. Weatheritt,‡ Holger Dinkel,† Markus Seiler,† Aidan Budd,† Toby J. Gibson,† and Norman E. Davey*.

TL;DR: The Eukaryotic Linear Motif resource is a manually curated database of short linear motifs (SLiMs) that contains more than 240 different motif classes with over 2700 experimentally validated instances.