K
Kirsten C Fertuck
Researcher at Harvard University
Publications - 2
Citations - 1502
Kirsten C Fertuck is an academic researcher from Harvard University. The author has contributed to research in topics: Regulation of gene expression & Estrogen receptor alpha. The author has an hindex of 2, co-authored 2 publications receiving 1423 citations. Previous affiliations of Kirsten C Fertuck include Boston College.
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Journal ArticleDOI
Genome-wide analysis of estrogen receptor binding sites
Jason S. Carroll,Clifford A. Meyer,Jun S. Song,Wei Li,Timothy R. Geistlinger,Jérôme Eeckhoute,Alexander S. Brodsky,Erika Krasnickas Keeton,Kirsten C Fertuck,Giles Hall,Qianben Wang,Stefan Bekiranov,Stefan Bekiranov,Victor Sementchenko,Edward A. Fox,Pamela A. Silver,Thomas R. Gingeras,X. Shirley Liu,Myles Brown +18 more
TL;DR: All estrogen receptor and RNA polymerase II binding sites are mapped on a genome-wide scale, identifying the authentic cis binding sites and target genes, in breast cancer cells, and distinct temporal mechanisms of estrogen-mediated gene regulation are demonstrated.
Journal ArticleDOI
Estrogen induces c-myc gene expression via an upstream enhancer activated by the estrogen receptor and the AP-1 transcription factor.
Chunyu Wang,Julie Ann Mayer,Abhijit Mazumdar,Kirsten C Fertuck,Kirsten C Fertuck,Heetae Kim,Myles Brown,Powel H. Brown +7 more
TL;DR: A novel pathway of estrogen regulation of gene expression by cooperation between ER and AP-1 at the distal enhancer element is demonstrated and it is shown thatAP-1 is involved in estrogen induction of the c-myc oncogene.